Search
Now showing items 1-6 of 6
Molecular Engineered Myoglobin With Unnatural Amino Acids As A Peroxidase
(Chemistry & Biochemistry, 2013-03-20)
Myoglobin (Mb) has been used as a model system to mimic other biologically important heme proteins like cytochrome P450 due to its ability to prepare mixed ligand complexes with different valencies, such as ferric, ferrous ...
Ruthenium(II) Polypyridyl Complexes As Potential Anticancer Drugs: Synthesis, Characterization, Cell Permeability And Investigation Of Their Hypoxia-selectivity
(Chemistry & Biochemistry, 2013-03-20)
Research on biological activity of ruthenium polypyridyl complexes (RPCs) continues to attract interest as these complexes have shown promising anti-cancer activity both in vitro and in vivo. The mononuclear RPC, ...
Ruthenium(II) Polypyridyl Complexes As Potential Anticancer Drugs: Synthesis, Characterization, Cell Permeability And Localization
(Chemistry & Biochemistry, 2013-07-22)
Research on biological activities of ruthenium polypyridyl complexes (RPCs) continues to attract interest as these complexes have shown promising anticancer activity both in vitro and in vivo.¹⁻³ The mononuclear ...
Increasing Lipophilicity Of Redox Active Ruthenium Complexes As A Means To Enhance Cytotoxicity And Reduce Animal Toxicity
(Chemistry & Biochemistry, 2013-03-20)
The dinuclear and monomeric ruthenium(II) polypyridyl complexes [(phen)2Ru(tatpp)Ru(phen)2]Cl4 (P) and monomer [(phen)2Ru(tatpp)]Cl2 (MP) are promising candidates for anticancer drug development in terms of the observed ...
A Non-heme Diiron Monooxygenase From Salmonella Typhimurium: Biochemical Characterization Of TRNA-modifying MiaE
(Chemistry & Biochemistry, 2013-07-22)
MiaE is a carboxylate bridged, non-heme diiron monooxygenase which catalyzes the O2-dependent hydroxylation of a hypermodified tRNA nucleoside at position 37 (2-methylthio-N-6-isopentenyl adenosine (37)-tRNA) [designated ...
Applications Of Circular Dichroism (CD) Spectroscopy As An Educational Tool For Undergraduate Students And Monitoring Protein Conformational Changes Induced By Ligand Binding
(Chemistry & Biochemistry, 2013-03-20)
The work reported here provides an overview on the applications of circular dichroism (CD) spectroscopy for the study of protein secondary structure. This project has two specific goals. First, to develop and validate an ...