MS Theses - DO NOT EDIT: Recent submissions
Now showing items 1-20 of 73
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Reactive Atmosphere Pyrolysis(RAP) of Silicon Carbo Nitride (SiCN)
(2023-08-17)Polymer Derived Ceramics (PDCs) are synthesized by converting liquid polymer precursors into ceramics through controlled pyrolysis. This study focuses on silicon carbonitride (SiCN) ceramics obtained from Ceraset Polysilazane ... -
Identification of acidic residues in proteins by selective chemical labeling and tandem mass spectrometry
(2023-08-15)**Please note that the full text is embargoed until 08/01/2025** Proteins play important role in carrying out a wide range of cellular activities. They are subjected to various post-translational modifications (PTMs) by ... -
Investigation of F420-dependent glucose-6-phosphate dehydrogenase variants using pH profiles and stopped-flow spectrometric ligand-binding methods
(2022-05-18)**Please note that the full text is embargoed until 5/17/2024** ABSTRACT: F420-dependent glucose-6-phosphate dehydrogenase (FGD) from Mycobacteria tuberculosis, catalyzes a reaction the conversion of glucose-6-phosphate ... -
An Investigation of Peak Shape Models in Chiral Separations
(2023-05-04)The use of superficially porous particles in chromatography has led to significant improvements in separation efficiency. However, peak asymmetry in enantiomeric separations causes performance comparisons across particle ... -
A Continuously Renewed Copper Electrode for Constant-Potential Amperometry
(2022-12-09)Pulsed amperometric detection (PAD) is a well-established technique used for the detection of electroactive compounds following Ion Chromatography (IC). Target analytes, such as carbohydrates and amino acids, typically ... -
Chemically Modified Cyclofructans for Sub/supercritical Fluid Chromatography and Hydrophilic Interaction Liquid Chromatography
(2022-08-16)Given the importance of supercritical fluid chromatography, several works focused on the application use different SFC stationary phases. In this work, two new derivatized cyclofructan bonded phases with superficially ... -
LnCrTeO6 (Ln= La, Pr, Nd) octahedral distortions and optical characterization
(2022-08-17)LnCrTeO6 (La, Pr, Nd) compounds are suspected to appear as vibrant blue-green colored materials. LnCrTeO6 (La, Pr, Nd) were synthesized to analyze the local coordination environments of Ln3+, Cr3+, and Te6+ cations. ... -
TUNING THE SOLUBILITY, CELLULAR-UPTAKE AND ACTIVITY OF MICROTUBULE STABILIZING RUTHENIUM POLYPYRIDYL COMPLEXES
(2021-08-06)Many Ru(II) Polypyridyl Complexes (RPCs) are being investigated as they show potent cytotoxicity and acceptable toleration in animals. Some of these RPCs are thought to target DNA and/or mitochondria in cells. Recently, ... -
CONTINUOUSLY RENEWED COPPER ELECTRODE FOR AMPEROMETRIC MEASUREMENT OF CARBOHYDRATES
(2021-08-05)Currently the benchmark method for carbohydrate analysis in a variety of application areas involves anion exchange chromatography followed by electrochemical detection at a gold electrode. The gold electrode surfaces foul ... -
STUDIES ON ENANTIOSELECTIVE DESYMMETRIZING ALKYNE HYDROSILYLATION
(2021-08-12)This research focuses on the design and synthesis of enantioselective desymmetrizing α-hydrosilylation of propargyl alcohols to provide α-hydroxy (E)-vinylsilanes. Transition metal-catalyzed, regio-and stereoselective ... -
INVESTIGATION OF THE CELLULAR UPTAKE AND CYTOTOXICITY OF RUTHENIUM(II) POLYPYRIDYL COMPLEXES AS A FUNCTION OF LIPOPHILICITY
(2022-05-17)Ru(II) polypyridyl complexes have been one of the focal points of investigation for inorganic anti-cancer drugs, as they are robust enough to remain chemically intact in vivo and many show potent cytotoxicty. In particular, ... -
Volatiles Characterization during Whiskey Production using Headspace - Solid Phase Microextraction - Gas Chromatography - Mass Spectrometry
(2021-12-21)Whiskey is the second most consumed distilled alcoholic beverage type, by brand, on the planet behind Chinese Baijiu. A prominent component in many varieties of whiskey, maize, contributes a wide profile of compounds that ... -
Headspace-Solid Phase Micro Extraction – Gas Chromatography – Mass Spectrometry (HS-SPME-GC-MS) Analysis for Oak Barrel Flavor Compounds in Whiskey
(2021-12-13)This study presents a method to simultaneously detect both fault compounds and oak barrel flavor compounds in whiskey using headspace-solid phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS). A major ... -
Synthesis of modified polydiacetylene (PDA) polymers for the detection of infective species
(2019-08-09)Polydiacetylene (PDAs) polymers are receiving more attention as biosensors due to their ability to change absorption and fluorescence properties upon sensing various chemical and physical changes in the environment. In ... -
3,5-Bis(3,5-bis(trifluoromethyl)phenyl)pyrazolyl complexes of Coinage Metals
(2018-05-16)Pyrazoles are an important class of five membered heterocyclic compounds consisting of two nitrogen atoms. Pyrazolate anions serve as useful ligands in coordination chemistry. When fluorinated substituents are attached to ... -
N-HETEROCYCLIC CARBENE AND BIS(PYRAZOLYL)METHANE SUPPORTED COPPER(I) AND SILVER(I) COMPLEXES OF ORGANOTRIFLUOROBORATES
(2019-05-23)Organotrifluoroborates have gone from capturing the imagination of the scientific community to being used extensively in a host of applications ranging from being employed to study boron intermediates to being used as a ... -
ENE REACTIONS OF METHYLIDENE THIAZOLIDINES
(2021-06-03)This thesis describes the synthesis of seven new racemic molecules from methylidene thiazolidines reacting with two enophiles, N-phenylmaleimide and ethyl glyoxylate. The synthesis of these molecules was achieved through ... -
Investigation of Computational Determination of Elastic Properties for Silicon Nitride and Silicon Carbonitride Materials
(2020-08-10)Silicon nitride and silicon carbonitride materials are versatile materials exhibiting useful properties at high temperatures and pressures. This study investigates the use of molecular dynamics simulations to determine ... -
The Effects of the Stereochemistry of Ruthenium (II) Polypyridyl Complexes on Microtubules as Targets for Chemotherapy
(2019-05-16)Ruthenium polypyridyl complexes (RPCs) are promising anticancer agents due to their robustness and tunability of their polypyridyl ligands. Their axial chirality generally allows for more selective binding to biological ... -
ENRICHMENT AND IDENTIFICATION OF DISULFIDE BONDED PEPTIDES BY TANDEM MASS SPECTROMETRY
(2017-08-09)Proteins are Comprised of different amino acids which can undergo various modifications known as post-translational modifications (PTMs). Amino acid’s side chains are the most common sites for the PTMs. Cysteine side chain ...