Browsing Theses and Dissertations(library) by Subject "Nanoparticles"
Now showing items 1-12 of 12
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AMORPHOUS SILICA BASED BIOMATERIALS FOR MUSCULOSKELETAL TISSUE REGENERATION APPLICATIONS
(2021-08-02)Musculoskeletal (MSK) injury includes any injuries that affect the bones, muscles, ligaments, tendons, or nerves. Open bone fracture is one of the common types of MSK traumatic injuries which results in not only bone ... -
DEVELOPMENT OF AN IN VITRO TBI MODELS AND VALIDATION OF NANODELIVERY FOR RESTORATION OF DISRUPTED BRAIN ENDOTHELIUM
(2019-09-06)Blast-induced traumatic brain injury (bTBI) is a serious concern among military personnel and their families. Although the mechanisms responsible for disruption to the brain are not well understood, the development of ... -
DEVELOPMENT OF PLASMA FUNCTIONALIZED NANO-ADDITIVES FOR OILS AND STUDY OF THEIR TRIBOLOGICAL PROPERTIES
(2017-10-20)Lubricants used in motor engines contain various chemical species to help enhance energy efficiency and provide increased longevity. Unfortunately, at the same time, these additives become a source of catalytic poisoning, ... -
ELEMENT-SPECIFIC NANOPARTICLE PLACEMENT TOWARD FABRICATING MULTI-ELEMENT METASTRUCTURES
(2019-05-17)Nanoscale entities such as semiconductor nanoparticles, magnetic nanoparticles, metal nanoparticles, and dielectric nanoparticles have attracted a lot of attention due to their novel electrical, optical, and magnetic ... -
INVESTIGATION OF THERMOPHYSICAL PROPERTIES OF ENHANCED MOLTEN SALT NANOFLUIDS FOR THERMAL ENERGY STORAGE (TES) IN CONCENTRATED SOLAR POWER (CSP) SYSTEMS
(2018-01-16)Concentrated solar power (CSP) technologies have a great economical and technical potential for energy production in future. Its incorporation with thermal energy storage (TES) overcomes one of the biggest challenges in ... -
LUNG CANCER TARGETED CHEMOTHERAPY VIA HERCEPTIN BASED CHIMERIC ANTIGEN RECEPTOR (CAR) ENGINEERED T CELL MEMBRANE COATED SYNTHETIC NANOPARTICLES
(2019-08-21)Cell membrane-derived nanoparticles recently caught attention due to their desirable features in drug delivery such as mimicking properties of native tissue and cells, avoiding systemic clearance, and alleviating foreign ... -
Nanoparticle-Mediated Controlled Myocardial Drug Delivery: A New Treatment for Hypertrophic Cardiomyopathy
(2020-09-04)Hypertrophic cardiomyopathy (HCM) is a genetic disease of the sarcomere, resulting in overgrowth of the septum that separates the left and right ventricles. HCM can affect as many as 1/200 people, making it the most common ... -
NANOPARTICLES FOR GENE THERAPY AND PROTEIN DELIVERY TO INDUCE ANGIOGENESIS AS AN ALTERNATIVE TREATMENT FOR PERIPHERAL ARTERIAL DISEASE
(2018-08-21)Peripheral arterial disease (PAD) is defined as a slow, progressive disorder of the lower extremity arterial vessels characterized by chronic narrowing that often results in occlusion and is associated with loss of functional ... -
SELF-INDUCED BACK ACTION ACTUATED NANOPORE ELECTROPHORESIS (SANE) SENSOR FOR MOLECULAR DETECTION AND ANALYSIS
(2019-05-15)We fabricated a novel single molecule nanosensor by integrating a Solid-State Nanopore (SSNP) and a Double Nanohole (DNH) nanoaperture. The nanosensor employs Self-Induced Back-Action (SIBA) for optical trapping and enables ... -
Stimuli-responsive nanoparticles for treatment of lung cancer
(2018-12-06)Despite extensive research and progress in anti-cancer therapeutics, an effective treatment for non-small cell lung cancer (NSCLC) remains elusive, resulting in poor 5-year patient survival rate. Towards this end, we have ... -
TARGETED DRUG-LOADED NANOPARTICLE SYSTEM (TDNPS) TO AMELIORATE AND TREAT IDIOPATHIC LUNG FIBROSIS
(2022-12-19)Idiopathic pulmonary fibrosis (IPF) is a fatal progressive disease with a dismal prognosis and 3-5 years of survival. Up to date, there are no effective treatments, and a few current therapies that do not ameliorate the ... -
Thermal Measurement and Optimization of Materials and Processes in a Li-ion Cell
(2017-08-02)Applications of Lithium-ion cells range from consumer electronics to electric cars because of their excellent electrochemical performance and energy density. However, a Li-ion cell also suffers from poor thermal transport ...