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AN ACTOMYOSIN DRIVEN, PRESSURE BASED ADHESION MODEL OF CONFINED GLIOBLASTOMA MULTIFORME CELL MIGRATION
(2016-05-13)
Glioblastoma multiforme (GBM) is the most aggressive and common form of glial tumors arising in the support cells of the brain. Cell migration plays a critical role in undermining the surgical resection of tumors. ...
Functional Studies of the Human Telomerase Holoenzyme
(2016-09-13)
Telomeres are the DNA structures that cap the ends of linear chromosomes. In humans, telomeres are composed of the hexameric repeats TTAGGG. The reverse transcriptase, telomerase maintains the telomeres by adding the TTAGGG ...
Localized Treatment of Malignant Melanoma Using a Modified Cellulose-Based Hydrogel Loaded with Temozolomide with Increased Safety of Human Dermal Fibroblasts and the Mechanisms Behind the Effect
(2021-08-30)
Melanoma pathophysiology is highly varied, and the initial cause of tumorigenesis is still unknown, but it is likely a combination of both epigenetic and genetic means. Further, melanoma tumors have one of the highest ...
DESIGNING REACTIVE OXYGEN SPECIES PRODUCING MATERIALS FOR CANCER AND WASTEWATER TREATMENTS
(2021-08-13)
This dissertation is focused on using nanotechnology to improve conventional photodynamic therapy (PDT) and advanced oxidation processes (AOPs) for cancer and wastewater treatments, respectively. Even though PDT has a great ...
DEVICES TO STUDY CANCER CELL BEHAVIOR
(2018-05-11)
Cancer is a major health concern that effects millions of people worldwide. The main contributing factor to the deadliness of the disease is cancer metastasis, where the cancer cells break away from the primary tumor site, ...
DEVELOPMENT OF DIAGNOSTIC PLATFORMS USING SMART TECHNOLOGIES
(University of Texas at Arlington Libraries, 2015-05)
Mortality rate of cancer has not significantly dropped over the past six decades because there is no effective tool for early detection. Likewise, mortality rate of cardiovascular (CV) disease remains alarming due to the ...
MAKING PUBLIC HEALTH PERFORMANCE MEASURES FOR TRANSPORTATION ACCESSIBLE TO PRACTITIONERS
Pollutants emitted into the atmosphere from static and mobile sources pose a threat to human health. The detrimental impact associated with air pollution varies by the type of pollutant, the magnitude, frequency and duration ...