Parameter Estimation in Illness-Death Processes: Preinfaractional Angina
An illness-death process is an absorbing Markov process where the illness states from the transient states of the process. This paper deals with the estimation of illness-death parameters from survivor data. The parameters of interest include the probabilities of recovery, relapse and death and mean residence times. The estimation problem is considered from the point of view of the theory of structural identifiability in compartmental analysis. As a prototypical example, we consider published data on preinfarctional angina.