Search
Now showing items 1-6 of 6
Novel Animal Model And In Vivo Imaging System To Study Inflammatory Response-mediated Cancer Metastasis
(Biomedical Engineering, 2010-07-19)
Cancer metastasis is the leading cause of death in cancer patients. A vast majority of cancer-related mortality is attributed to this rather than the primary tumor itself, making the understanding of cancer metastasis ...
Advances In Helical Stent Design And Fabrication: Studies Of Stent Thermal Treatment, Stent Mechanical Properties, And Stent Interactions With A Simulated Plaque-laden Artery
(Biomedical Engineering, 2010-11-01)
Advancements in processing biomaterials have lead to the development of bioresorbable PLLA drug-loaded stents with different geometric configurations. To further advance the technology, systematic studies have been carried ...
Multi-ligand Nanoparticles For Targeted Drug Delivery To The Injured Vascular Wall
(Biomedical Engineering, 2010-11-01)
Pathological conditions like coronary artery disease, acute myocardial infarction, stroke, and peripheral artery diseases as well as cardiovascular interventions used in the treatment of coronary artery diseases such as ...
Targeted Delivery Of Carbon Nanotubes To Cancer Cells
(Biomedical Engineering, 2010-07-19)
CD22 is broadly expressed on human B cell lymphomas. Monoclonal anti-CD22 antibodies (MAbs) alone, or coupled to toxins, have been used to selectively target these tumors both in severe combined immunodeficient (SCID) mice ...
Enhanced Endothelialization On Surface Modified Poly(L-lactic Acid)
(Biomedical Engineering, 2010-07-19)
Current synthetic vascular grafts and polymer-coated drug-eluting stents (DES) have certain limitations, such as thrombosis and restenosis due to the incomplete recovery of vascular endothelial cells on their luminal sides. ...
Mechanisms Of Biomaterial Mediated Fibrotic Responses And Strategies To Improve Tissue Reactions To Biomaterial Implants
(Biomedical Engineering, 2010-07-19)
Despite considerable advancements in biomaterial synthesis and modification techniques, most tissue engineering scaffolds elicit fibrotic reactions resulting in implant encapsulation, secluding cells and/or therapeutic ...