Now showing items 1-10 of 10

    • Direct current electrical characterization of ds-DNA in nanogap junctions 

      Iqbal, Samir M.; Balasundaram, G.; Bashir, R.; Bergstrom, D. E.; Ghosh, Subhasis (Copyright American Institute of Physics;Department of Electrical Engineering, 2005-04-05)
      Measurements of DNA conductivity, hybridization, and melting using electronic means can have wide applications in molecular electronics and biological sensors. We have fabricated nanogap break-junctions by electromigration ...
    • Electrical detection of single-base DNA mutation using functionalized nanoparticles 

      Iqbal, Samir M.; Christensen, Shawn; Goyal, Swati; Noor, Mohammud R. (Copyright American Physical Society,Department of Electrical Engineering, The University of Texas at Arlington, 2009-08-17)
      We report an electrical scheme to detect specific DNA. Engineered hairpin probe DNA are immobilized on a silicon chip between gold nanoelectrodes. Hybridization of target DNA to the hairpin melts the stem nucleotides. Gold ...
    • Fabrication and characterization of solid-state nanopores using a field emission scanning electron microscope 

      Iqbal, Samir M.; Chang, H.; Bashir, R.; Stach, E. A.; King, A.H.; Zaluzec, N. J. (Copyright American Institute of Physics, 2006-03-08)
      The fabrication of solid-state nanopores using the electron beam of a transmission electron microscope (TEM) has been reported in the past. Here, we report a similar method to fabricate solid-state nanopores using the ...
    • A mesoscale model of DNA interaction with functionalized nanopore 

      Iqbal, Samir M.; Liu, Yaling (Copyright American Physical Society,Department of Electrical Engineering, The University of Texas at Arlington, 2009-11-30)
      Functionalized nanopores have been used recently for the detection of specific DNA. The interactions between the DNA and the nanopore are not well understood due to the small size of DNA/nanopore and dynamic translocation ...
    • Microheater platform for selective detachment of DNA 

      Iqbal, Samir M.; Jain, Ankur; Javed, Annas (American Institute of Physics;Department of Electrical Engineering, University of Texas at Arlington, 2012-08-30)
      Despite deoxyribonucleic acid (DNA)’s well-known temperature sensitivity, not much work has been reported on leveraging temperature to manipulate the interaction of DNA with surfaces. This paper describes a microheater ...
    • Nanostructures for Medical Diagnostics 

      Bellah, Motasim; Christensen, Shawn; Iqbal, Samir M. (Hindawi Publishing Corporation;Department of Electrical Engineering, University of Texas at Arlington, 2011-10-19)
      Nanotechnology is the art of manipulating materials on atomic or molecular scales especially to build nanoscale structures and devices. The field is expanding quickly, and a lot of work is ongoing in the design, characterization, ...
    • Porous Organic Nanolayers for Coating of Solid-state Devices 

      Iqbal, Samir M.; Asghar, Waseem; Vidyala, Sri Divya (BioMed Central ;Department of Electrical Engineering, University of Texas at Arlington, 2011-05-14)
      Highly hydrophobic surfaces can have very low surface energy and such low surface energy biological interfaces can be obtained using fluorinated coatings on surfaces. Deposition of biocompatible organic films on solid-state ...
    • Self-assembled synthesis and characterization of microchannels in polymeric membranes 

      Iqbal, Samir M.; Kahsai, Wintana T.; Pham, Uyen H. T.; Sankaran, Jeyantt S. (American Institute of Physics,Department of Electrical Engineering, University of Texas at Arlington, 2012-07-19)
      This article describes a novel self-assembly approach to create microchannels in polydimethylsiloxane (PDMS) membranes using poly(ethylene oxide) (PEO) and polyurethane (PU). The interactions between hydrophilic PEO/PU ...
    • Shrinking of Solid-state Nanopores by Direct Thermal Heating 

      Iqbal, Samir M.; Asghar, Waseem; Billo, Joseph A.; Ilyas, Azhar (Asghar et al;SpringerOpen;Department of Electrical Engineering, University of Texas at Arlington, Arlington, 2011-05-04)
      Solid-state nanopores have emerged as useful single-molecule sensors for DNA and proteins. A novel and simple technique for solid-state nanopore fabrication is reported here. The process involves direct thermal heating of ...
    • Viscosity and surface-free energy effects in thermal shrinking of solid-state nanopores 

      Iqbal, Samir M.; Asghar, Waseem; Billo, Joseph A.; Carter, Ronald L.; Jones, Jared (American Institute of Physics;Department of Electrical Engineering, University of Texas at Arlington, 2012-06-05)
      Solid-state nanopores are fabricated by either drilling these in thin membranes or by shrinking large pores with electron/ion beam. Simple heating of thin membranes with many large pores has been shown recently to controllably ...