Browsing Department of Chemistry and Biochemistry by Title
Now showing items 72-91 of 247
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Effect Of Structure And Stereochemistry On Cytotoxicity Of Ruthenium Polypyridyl Complexes
(Chemistry & Biochemistry, 2007-08-23)Efforts to develop novel non-platinum, metal-based antitumor drugs have been pursued by many groups and ruthenium complexes have drawn a lot of attention as prospective transition metal-based antineoplastic agents. Recently, ... -
ELECTROCHEMICAL AND PHOTOELECTROCHEMICAL PROPERTIES OF OXIDE AND CHALCOGENIDE SEMICONDUCTORS
(2020-12-08)Photoelectrochemical (PEC) water splitting via inorganic semiconductors has shown interest in technical applications such as harvesting sunlight as sustainable fuels. Chalcogen-based (S, Se, Te) semiconductors are important ... -
Electrolysis Of Coal And Carbon Slurry Suspensions
(Chemistry & Biochemistry, 2013-03-20)In this dissertation study, different ranks of coal and carbons were tested as anode depolarizers in a three electrode electrochemical cell designed for hydrogen generation. The focus of this study was mainly Texas lignite ... -
Electrowetting Of Ionic Liquids And Development Of An Electrowetting Based Tunable RC Filter And Its Uses As An Analytical Detector
(Chemistry & Biochemistry, 2011-09-12)Wettability control of a liquid drop by an external electric field or "electrowet- ting" recently was the subject of special interest among researchers due to its util- ity for a variety of applications. Some of these ... -
Elucidation Of The Structure And Recognition Properties Of Antimony(III)-tartrate Using Electrospray Ionization Mass Spectrometry
(Chemistry & Biochemistry, 2010-11-01)Chirality of molecules is a major topic in the design, discovery and development of new drugs. Currently, analytical chemistry research divisions are challenged to find new methods to screen enantiospecific molecular ... -
Enantiomeric Chromatographic Separations And Ionic Liquids In Gas Chromatography
(Chemistry & Biochemistry, 2010-07-19)Due to the different therapeutic values of optical isomers, the production of enantiomerically pure drugs is of growing demand in pharmaceutical, biotechnology, and agrochemical industries. Today, gas chromatography (GC) ... -
Enantiomeric Separation, Microorganism Studies And Determination Of Binding Constants Using Capillary Electrophoresis
(Chemistry & Biochemistry, 2010-03-03)Enantiomeric separation of three series of compounds, including β-lactams, synthetic amino acids and ruthenium(II) polypyridyl complexes using different modes of capillary electrophoresis are discussed in this dissertation. ... -
Enantiomeric Separations And New Chiral Stationary Phases
(Chemistry & Biochemistry, 2010-03-03)Chirality is an important concern for biological activity because asymmetry dominates biological processes at a molecular level. After nearly thirty years of development, liquid chromatographic separations on chiral ... -
ENANTIOSELECTIVE SYNTHESIS OF AN ANTICANCER RUTHENIUM POLYPYRIDYL COMPLEX (RPC) AND INFLUENCE OF CHIRAL SELECTIVITY ON DNA PHOTOCLEAVAGE
(2017-12-08)Ruthenium polypyridyl complexes (RPCs) represent a promising therapeiutic class of drugs for transition-metal based anticancer drug development. The complex [(phen)2Ru(tatpp)Ru(phen)2] (44+) is a RPC which has shown success ... -
ENE REACTIONS OF METHYLIDENE THIAZOLIDINES
(2021-06-03)This thesis describes the synthesis of seven new racemic molecules from methylidene thiazolidines reacting with two enophiles, N-phenylmaleimide and ethyl glyoxylate. The synthesis of these molecules was achieved through ... -
ENRICHMENT AND IDENTIFICATION OF DISULFIDE BONDED PEPTIDES BY TANDEM MASS SPECTROMETRY
(2017-08-09)Proteins are Comprised of different amino acids which can undergo various modifications known as post-translational modifications (PTMs). Amino acid’s side chains are the most common sites for the PTMs. Cysteine side chain ... -
EPIGENETIC MECHANISM OF REGULATION OF HOX GENES AND NEUROTRANSMITTERS VIA HORMONES AND LncRNA
(2017-08-02)Endocrine disrupting chemicals (EDCs) are classes of environmental contaminants whose exposure even at very low concentrations interfere with normal endocrine signaling and induce many adverse health effects including ... -
Epigenetics Of HOXC13 Endocrine Regulation And Its Role In Gene Expression And Tumorigenesis
(Chemistry & Biochemistry, 12-10-2012)HOX genes are a subgroup of homeobox containing gene superfamily and have crucial roles in cell proliferation, cell differentiation, and embryonic development. HOXC13, one of 39 identified human HOX genes, is involved in ... -
EPIMERIC PEPTIDES IN ALZHEIMER’S DISEASE: IMPLICATIONS FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY AND IMMUNOTHERAPIES
(2023-05-19)Evidence has shown that the extracellular deposition of amyloid-beta (Aβ) peptide is a contributing factor of Alzheimer’s disease. Further, modifications to Aβ peptides may enhance the deposition of Aβ plaques and/or ... -
Estrogen Analysis By Liquid Chromatography - Mass Spectrometry
(Chemistry & Biochemistry, 2011-03-03)Estrogens are well known as female hormones associated with both health and disease. Although they have been reported as potential carcinogens, their use as therapy in the treatment of neurodegeneration has recently received ... -
EVALUATION OF ACTIVATED CARBON AS A COMMERCIAL DRUG DISPOSAL PRODUCT USING LIQUID CHROMATOGRAPHY–TANDEM MASS SPECTROMETRY
(2015-11-18)At present, pharmaceuticals, synthetic organic compounds, and endocrine disrupting compounds are ubiquitous in our environment. These have been introduced by consumers and manufacturers directly and indirectly for decades. ... -
Examining Ruthenium Chromophores For The Photochemical Reduction Of CO₂To Methanol
(Chemistry & Biochemistry, 2014-03-12)Our consumption of energy for transportation and electricity has been growing as quickly as our population. As this demand for energy increases we increase our production of carbon dioxide by the burning of fossil fuels ... -
EXPEDITIOUS APPROACH TO 3,3’-BIS-SILYL BINOLS, BIPHENOLS, AND 3,3’-BIS-SILYL PHOSPHORAMIDITES ENABLED BY CATALYTIC C–H SILYLATION WITH A TRACELESS ACETAL DIRECTING GROUP
(2021-05-10)The research described in this dissertation is on two different projects namely i) Syntheses of 3,3’-bis functionalized BINOL and biphenol compounds, ii) Syntheses of 3,3’-bis silyl-BINOL-based phosphoramidites. The first ... -
EXPLORING FLEXIBLE CONFIGURATIONS OF A CUSTOM MULTIPATH LC –MS FOR SMALL MOLECULES AND PROTEIN ANALYSIS
(2017-08-07)There are diseases where both small molecules and proteins are found as disease indicators. In the usual analysis of small molecules, proteins are precipitated out during the sample preparation. In the small molecule ... -
FLUORINATED ALCOHOL INDUCED SUPRAMOLECULAR BIPBASIC SYSTEMS IN PROTEOMICS AND LIPIDOMICS
(2021-05-28)The Fluoroalcohol induced Supramolecular Biphasic (FAiS-BP) systems are composed of a supramolecular phase which is a highly concentrated mixture of a fluoroalcohol and an amphiphile, and a separate aqueous-rich phase. The ...