Browsing Department of Chemistry and Biochemistry by Author "Awasthi, Sanjay"
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Novel Functions And Physiological Significance Of Ral Interacting Protein - RLIP76 In In Vitro And In Vivo Models
Zajac, Ewa L (Chemistry & Biochemistry, 2007-08-23)This dissertation is divided into four parts. The first part is an introduction of energy dependent xenobiotic transporters and their relevance in multidrug resistance. However, the main focuse is the description of RLIP76 ... -
Ral Interacting Protein (Ralbp1): Linking Glutathione Conjugate Transport To Oxidative Stress Defenses And Signaling Pathways
Wickramarachchi, Dilki (Chemistry & Biochemistry, 2008-08-08)The glutathione-conjugate transporter protein DNP-SG ATPase was demonstrated to be identical to the independently cloned Ral-effector, Ralbp1. Glutathione-conjugate transport is linked to substrate-stimulated ATPase activity, ... -
Ralbp1 In Stress Resistance
Drake, Kenneth (Chemistry & Biochemistry, 2008-08-08)Ralbp1 is a multi-specific transporter of glutathione conjugates as well as unconjugated amphiphilic toxins. Because glutathione conjugates are major metabolites of toxic lipid peroxidation products generated as a consequence ...