Browsing by Author "Cho, Michael"
Now showing items 1-9 of 9
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DEVELOPMENT OF AN IN VITRO TBI MODELS AND VALIDATION OF NANODELIVERY FOR RESTORATION OF DISRUPTED BRAIN ENDOTHELIUM
Inyang, Edidiong I; 0000-0002-6639-6541 (2019-09-06)Blast-induced traumatic brain injury (bTBI) is a serious concern among military personnel and their families. Although the mechanisms responsible for disruption to the brain are not well understood, the development of ... -
FORMATION AND MORPHOLOGICAL CHANGES OF STRESS ACTIN FILAMENTS IN ADIPOSE-DERIVED STEM CELLS
Priester, Adam; 0009-0006-6860-1058 (2023-12-18)Adipose-Derived Stem Cells (ADSCs) are a sub-type of stem cell that can be collected and isolated from the adipose tissue. Adipogenesis describes the commitment and differentiation of stem cells, including ADSCs, toward ... -
MODULATION OF PHYSIOLOGIC RESPONSES OF INSULIN SECRETING CELLS USING ELECTRICAL AND PHOTOSTIMULATION
Liebman, Caleb Nathaniel; 0000-0002-7871-3436 (2020-09-01)Islet transplantation is a surgical procedure aimed at providing insulin independence to those suffering with Type I diabetes. Prior to implantation, a therapeutic window exists ex vivo where the cells can be treated in ... -
NANOPARTICLES FOR GENE THERAPY AND PROTEIN DELIVERY TO INDUCE ANGIOGENESIS AS AN ALTERNATIVE TREATMENT FOR PERIPHERAL ARTERIAL DISEASE
Noukeu, Linda Christellia (2018-08-21)Peripheral arterial disease (PAD) is defined as a slow, progressive disorder of the lower extremity arterial vessels characterized by chronic narrowing that often results in occlusion and is associated with loss of functional ... -
PHOTOBIOMODULATION AND STEM CELL DIFFERENTIATION: APPLICATION TO MODULATE ADIPOGENESIS THROUGH CELLULAR AND NUCLEAR MORPHOLOGY
Mccolloch, Andrew Redmond (2020-05-28)Mesenchymal stem cells (MSCs) are of great interest in regenerative medicine due to their capability to self-renew and differentiate to various lineages. Typically, differentiation to specific cell types has relied on ... -
PHOTOBIOMODULATION OF NEURAL STEM CELL DIFFERENTIATION USING INFRARED (810 NM) LASER STIMULATION
Salgado Cordova, Noemi (2021-05-07)The standardized clinical use of photobiomodulation (PBM) across many applications has been obstructed due to the lack of understanding in how each of the parameters affect the end results. Although the optimal parameters ... -
PHOTOMODULATORY EFFECTS ON INSULIN SECRETING BETA CELLS
Loya, Sheccid Alejandra; 0000-0001-7159-9477 (2021-05-06)Diabetes mellitus is a chronic metabolic disease characterized by increased blood glucose levels and affects more than 8% of people worldwide (Rutter et. al, 2015). Typically, diabetes is divided into two large subcategories: ... -
The Biomechanics of Cardiac Elastin and its Role in Bioengineering
McMahan, Sara R.; 0000-0001-6712-3353 (2020-09-09)Elastin is an essential structural protein responsible for the elasticity of many tissues, including skin, lungs, blood vessels, and other highly dynamic tissues and organs in the body. In the heart, cardiac elastin has ... -
THE EFFECTS OF POLOXAMER 188 ON WOUND CLOSURE IN A MOUSE BRAIN ENDOTHELIUM MODEL
Grubbs, Mia Claire; 0009-0006-8837-864X (2023-12-11)The blood-brain barrier (BBB) plays a crucial role in maintaining central nervous system homeostasis and, if structurally and functionally compromised, can lead to severe neurological consequences. This thesis explores the ...