Browsing by Author "Iqbal, Samir M."

Now showing items 1-20 of 29

    • DEVELOPMENT OF DIAGNOSTIC PLATFORMS USING SMART TECHNOLOGIES 

      Bellah, Md Motasim (University of Texas at Arlington Libraries, 2015-05)
      Mortality rate of cancer has not significantly dropped over the past six decades because there is no effective tool for early detection. Likewise, mortality rate of cardiovascular (CV) disease remains alarming due to the ...

    • DEVICES TO STUDY CANCER CELL BEHAVIOR 

      Abdallah, Mohammad G.; 0000-0003-4447-2547 (2018-05-11)
      Cancer is a major health concern that effects millions of people worldwide. The main contributing factor to the deadliness of the disease is cancer metastasis, where the cancer cells break away from the primary tumor site, ...

    • Direct current electrical characterization of ds-DNA in nanogap junctions 

      Iqbal, Samir M.; Balasundaram, G.; Bashir, R.; Bergstrom, D. E.; Ghosh, Subhasis (Copyright American Institute of Physics;Department of Electrical Engineering, 2005-04-05)
      Measurements of DNA conductivity, hybridization, and melting using electronic means can have wide applications in molecular electronics and biological sensors. We have fabricated nanogap break-junctions by electromigration ...

    • EARLY DETECTION OF METASTATIC CANCER USING COMPUTATIONAL ANALYSIS 

      Mansur, Nuzhat (2017-10-06)
      Metastasis is the leading cause of cancer related deaths. Early detection of cancer cells can enable early disease diagnosis and stage specific therapeutics. Metastatic cancer cells have abnormal expression of certain ...

    • Electrical Detection Of Single-based DNA Mutation Using Functionalized Nanoparticles 

      Noor, Mohammud R. (Electrical Engineering, 2010-03-03)
      DNA molecules posses unique structure and molecular recognition properties that makes them excellent candidate for bio-chemical sensors. Understanding the mechanism of charge transport in DNA is essential to develop DNA ...

    • Electrical Apparoaches For Selective Detection Of Cancer Biomarker Proteins With Aptamers 

      Pachampettai Ramachandran, Priyanka (Biomedical Engineering, 2010-03-03)
      Cancer is a disease that is the central focus of many a researcher's attention. As it is a disease that can spread very rapidly and can be fatal in many cases, its early detection and early treatment can dramatically change ...

    • Electrical detection of single-base DNA mutation using functionalized nanoparticles 

      Iqbal, Samir M.; Christensen, Shawn; Goyal, Swati; Noor, Mohammud R. (Copyright American Physical Society,Department of Electrical Engineering, The University of Texas at Arlington, 2009-08-17)
      We report an electrical scheme to detect specific DNA. Engineered hairpin probe DNA are immobilized on a silicon chip between gold nanoelectrodes. Hybridization of target DNA to the hairpin melts the stem nucleotides. Gold ...

    • Electronic Biosensors for Early Cancer Detection 

      Ali, Waqas; 0000-0001-8293-1789 (2016-05-06)
      Nanotechnology is an emerging field that holds promise to improved disease diagnosis and better health care. It has revolutionized the medical industry and is continuing to mesmerize in other research areas as well. Even ...

    • Fabrication and characterization of solid-state nanopores using a field emission scanning electron microscope 

      Iqbal, Samir M.; Chang, H.; Bashir, R.; Stach, E. A.; King, A.H.; Zaluzec, N. J. (Copyright American Institute of Physics, 2006-03-08)
      The fabrication of solid-state nanopores using the electron beam of a transmission electron microscope (TEM) has been reported in the past. Here, we report a similar method to fabricate solid-state nanopores using the ...

    • Fabrication and modification of implantable micro-probes for neuro-studies 

      Cao, Hung Viet (2014-09-17)
      In this work, different types of implantable probes fabricated on Si and polyimide substrates for sensing neurotransmitters, recording extracellular action potentials and stimulating the neurons have been developed. Several ...

    • A mesoscale model of DNA interaction with functionalized nanopore 

      Iqbal, Samir M.; Liu, Yaling (Copyright American Physical Society,Department of Electrical Engineering, The University of Texas at Arlington, 2009-11-30)
      Functionalized nanopores have been used recently for the detection of specific DNA. The interactions between the DNA and the nanopore are not well understood due to the small size of DNA/nanopore and dynamic translocation ...

    • Micro-device For Selective Isolation And Cytology Of Cancer Cells 

      Wan, Yuan (Biomedical Engineering, 2012-07-25)
      Early detection and isolation of circulating tumor cells (CTCs) can enable early cancer diagnosis and more effective therapeutics. Aptamers have emerged as probe molecules that have binding affinities comparable to antibodies ...

    • Microfluidic Chip-based Fabrication Of Hollow Alginate Microfiber For Enzyme Entrapment And Reaction 

      Pham, Uyen Hoang Thao (Biomedical Engineering, 2014-09-17)
      This thesis demonstrates a simple process to generate alginate hollow microfibers by using a non-lithographic PDMS microfluidic device. The microfluidic device was fabricated by a novel template method in a wet lab without ...

    • Microheater platform for selective detachment of DNA 

      Iqbal, Samir M.; Jain, Ankur; Javed, Annas (American Institute of Physics;Department of Electrical Engineering, University of Texas at Arlington, 2012-08-30)
      Despite deoxyribonucleic acid (DNA)’s well-known temperature sensitivity, not much work has been reported on leveraging temperature to manipulate the interaction of DNA with surfaces. This paper describes a microheater ...

    • Molecular And Textural Surface Engineering For Biological Sensing 

      Mahmood, Mohammed Arif Iftakher
      This research work was aimed at finding novel approaches for early cancer detection. In cancer diagnosis, the candidate molecules largely include free DNA, related proteins and tumor cells, listed in increasing order of ...

    • MOLECULARLY ENGINEERED SURFACES FOR EARLY CANCER DIAGNOSIS 

      Hasan, Mohammad Raziul; 0000-0001-6761-4582 (2018-01-08)
      Early detection of cancer can have immediate and significant impact on effective treatments for cancer patients and better disease prognosis. In the early stage of cancer, symptoms are initially expressed at molecular and ...

    • Nanogap Break Junctions And Solid-state Micropores As Electronic Biosensors 

      Ilyas, Azhar (Electrical Engineering, 2014-03-12)
      Cancer has been the top ranked fatal disease for the last several decades. Most of the cancers remain silent at its earlier stage and are usually diagnosed at advanced and incurable phase. Early detection of cancer can ...

    • NANOPORE BIOSENSORS FOR MOLECULAR DETECTION AND ANALYSIS 

      Raza, Muhammad Usman; 0000-0003-4276-5573 (2018-05-17)
      Nanoscale fabrication techniques have led the march towards a new class of biosensors that were not possible to build in the past due to technological limitations. These molecular nanosensors can have biochemical, ...

    • Nanoscale Approaches For Biomolecule Separation And Detection 

      Goyal, Swati (Biomedical Engineering, 2010-03-03)
      Nanotechnology has the potential to contact and impact the biological interactions at the most basic chemical and physical levels. New approaches to nanodevices allow high sensitivity and specificity with low sample ...

    • Nanostructures for Medical Diagnostics 

      Bellah, Motasim; Christensen, Shawn; Iqbal, Samir M. (Hindawi Publishing Corporation;Department of Electrical Engineering, University of Texas at Arlington, 2011-10-19)
      Nanotechnology is the art of manipulating materials on atomic or molecular scales especially to build nanoscale structures and devices. The field is expanding quickly, and a lot of work is ongoing in the design, characterization, ...