Browsing by Author "Lovely, Carl"
Now showing items 1-15 of 15
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APPLICATION OF NOVEL HETEROSUBSTITUTED VINYLIMIDAZOLES: AN APPROACH EN ROUTE TO THE TOTAL SYNTHESIS OF AXINELLAMINE A
Ray, Abhisek; 0000-0002-0088-0576 (2016-05-11)Our group is primarily interested in the total synthesis of oroidin-based pyrrole-imidazole-containing marine sponge-derived alkaloids. These pyrrole-imidazole natural products are a growing class of alkaloids with exotic ... -
Application Of Pd-catalyzed Reactions In The Total Synthesis Of Oroidin-derived Alkaloids
Bhandari, Manojkumar R. (Chemistry & Biochemistry, 2014-03-17)The oroidin family of marine natural products is a growing group of sponge-derived alkaloids which contain 2-aminoimidazole and pyrrolecarboxamide fragments as their signature features. Due to their structural diversity ... -
Approaches Toward the Total Synthesis of Oroidin Alkaloids:Nagelamide A, C and Ageliferin
Herath, Apsara (2018-05-25)Nagelamides and ageliferin are oroidin-derived alkaloids which have gained the attention of the scientific community, because of their significant biological activity as well as the unprecedented structural diversity. Our ... -
DESIGN, SYNTHESIS AND APPLICATIONS OF BIOMIMETIC FLAVIN-BASED ORGANOCATALYSTS
Hossain, Mohammad Shawkat (University of Texas at Arlington Libraries, 2015-12)Oxidation reactions are one of the most important transformations in synthetic chemistry. Most commonly used oxidants are metal oxides, which are neither green nor selective towards multi-functional molecules. The efficiency ... -
Leveraging propargylic frameworks in the total synthesis of natural products containing a 2-aminoimidazole
Singh, Ravi P.; 0000-0002-2900-5855 (2019-08-30)Our group is mainly interested in the total synthesis of marine sponge-derived 2-aminoimidazole-containing alkaloids. A new family of 2-aminoimidazole alkaloids, the Leucetta alkaloids, is a group of >60, 2-aminoimidazole ... -
New Applications Of The Pauson-Khand Reaction And Studies Towards The Synthesis Of The Hamigerans
Madu, Christian Emeka (Chemistry & Biochemistry, 2007-09-17)This dissertation is divided into two parts. The first part describes the dicobalt octacarbonyl mediated synthesis of medium sized rings via intramolecular Pauson-Khand (IMPK) reaction. The cyclization of 1,8-enynes has ... -
NEW STRATEGIES FOR CATALYTIC C-H AND OLEFIN HYDROSILYLATION
Asgari, Parham; 0000-0002-2280-0960 (2018-08-23)In the works described here, new catalytic hydrosilylation strategies were explored. First, a highly selective, bond functionalization strategy, achieved via relay of two transition metal catalysts and use of traceless ... -
Ring Closing Enyne Metathesis Of Imidazole Derivatives And Subsequent Diels-Alder Reaction
Ekanayake, E. Vindana (Chemistry & Biochemistry, 2008-08-08)The work presented in this thesis describes the development of new synthetic routes to elaborate simple imidazole derivatives into complex imidazole molecules by the application of different sequential transformations. The ... -
Studies Toward The Enantioselective Total Synthesis Of The Martinella Alkaloids
Badarinarayana, Vivek (Chemistry & Biochemistry, 2007-08-23)This dissertation consists of two parts. The first part describes the enantioselective total synthesis of martinellic acid. The Martinella alkaloids have attracted considerable attention in the synthetic community over the ... -
Studies Towards Bioactive Imidazoles
Koda, Karuna (Chemistry & Biochemistry, 2008-04-22)The work presented in this thesis focuses on the development of an enantioselective and practical route form the total synthesis of villagorgin via haplosleridamine imidazole alkaloid containing β- carboline moiety by ... -
Synthesis and Function of Ion-Selective Single-Molecule Fluorescent Imaging Molecules and Materials
Denisenko, Alena A; 0000-0002-8093-6858 (2022-05-18)Neutrinos are fermion subatomic particles that interact only by weak subatomic forces—making them almost impossible to detect. However, they can be produced in specific radioactive decay reactions, such as beta decay. We ... -
Synthetic Studies And Biological Evaluation Of Imidazole-containing Marine Alkaloids
Schmid, Lesley Ann (Chemistry & Biochemistry, 2008-08-08)This dissertation discusses the synthetic methods towards and the preliminary biological studies of an unnamed, imidazole-containing alkaloid, derived from the marine species Oceanapia. This alkaloid was first discovered ... -
Total Synthesis Of 2-aminoimidazole Alkaloids From Leucetta And Clathrina Sponges
Koswatta, Panduka B. (Chemistry & Biochemistry, 2010-07-19)Sponges of the major class, Calcarea can be found in nearly all marine habitats. Two Calcarea genera, Leucetta and Clathrina have found be rich with 2-aminoimidazole alkaloids. The first alkaloid of these groups was isolated ... -
Total Synthesis Of Cyclooroidin And Studies Towards Some Oroidin Dimers
Mukherjee, Sabuj (Chemistry & Biochemistry, 2010-07-19)This dissertation consists of two parts. The first part describes the synthesis of northern fragment of nagelamide R and the enantioselective total synthesis of cyclooroidin. The oroidin family of marine natural products ... -
Total Synthesis Of Marine Derived Natural Products: Kealiiquinone And Ageliferin
Lima, Heather Marie (Chemistry & Biochemistry, 2014-03-17)An intramolecular Diels-Alder reaction of vinylimidazoles has been developed and applied towards the total synthesis of benzimidazole and tetrahydrobenzimidazole natural products, namely kealiiquinone and ageliferin. A ...