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Electrical Detection Of Single-based DNA Mutation Using Functionalized Nanoparticles
(Electrical Engineering, 2010-03-03)
DNA molecules posses unique structure and molecular recognition properties that makes them excellent candidate for bio-chemical sensors. Understanding the mechanism of charge transport in DNA is essential to develop DNA ...
Electrical detection of single-base DNA mutation using functionalized nanoparticles
(Copyright American Physical Society,, 2009-08-17)
We report an electrical scheme to detect specific DNA. Engineered hairpin probe DNA are immobilized on a silicon chip between gold nanoelectrodes. Hybridization of target DNA to the hairpin melts the stem nucleotides. Gold ...