Search
Now showing items 1-7 of 7
APPLICATION OF NOVEL HETEROSUBSTITUTED VINYLIMIDAZOLES: AN APPROACH EN ROUTE TO THE TOTAL SYNTHESIS OF AXINELLAMINE A
(2016-05-11)
Our group is primarily interested in the total synthesis of oroidin-based pyrrole-imidazole-containing marine sponge-derived alkaloids. These pyrrole-imidazole natural products are a growing class of alkaloids with exotic ...
NEW STRATEGIES FOR HYDROSILYLATION OF PROPARGYL ALCOHOLS, OLEFIN POLYMERIZATION AND ON-CHIP ORGANIC SYNTHESIS
(2020-08-11)
The research described in this dissertation is on three different projects namely i) design and synthesis of traceless hydrosilyl acetal-directed, exo-syn hydrosilylation of propargyl alcohols to produce α-hydroxy ...
STUDIES ON ENANTIOSELECTIVE DESYMMETRIZING ALKYNE HYDROSILYLATION
(2021-08-12)
This research focuses on the design and synthesis of enantioselective desymmetrizing α-hydrosilylation of propargyl alcohols to provide α-hydroxy (E)-vinylsilanes. Transition metal-catalyzed, regio-and stereoselective ...
NEW STRATEGIES FOR CATALYTIC C-H AND OLEFIN HYDROSILYLATION
(2018-08-23)
In the works described here, new catalytic hydrosilylation strategies were explored. First, a highly selective, bond functionalization strategy, achieved via relay of two transition metal catalysts and use of traceless ...
SYNTHETIC AND MECHANISTIC INVESTIGATIONS OF RUTHENIUM ALKYLIDENE-CATALYZED ALKENE-SILANE CROSS-COUPLING REACTIONS
(2017-12-18)
Grubbs-type ruthenium alkylidene-catalyzed intramolecular alkene hydrosilylation and intermolecular dehydrogenative silylation and hydrosilylation of vinylarenes have been achieved with high regio- and stereoselectivity. ...
EXPEDITIOUS APPROACH TO 3,3’-BIS-SILYL BINOLS, BIPHENOLS, AND 3,3’-BIS-SILYL PHOSPHORAMIDITES ENABLED BY CATALYTIC C–H SILYLATION WITH A TRACELESS ACETAL DIRECTING GROUP
(2021-05-10)
The research described in this dissertation is on two different projects namely i) Syntheses of 3,3’-bis functionalized BINOL and biphenol compounds, ii) Syntheses of 3,3’-bis silyl-BINOL-based phosphoramidites. The first ...
Controlled Hydrosilylations of Carbonyl Compounds and Computational Investigations of a Hydride Shuttle Mechanism for Alkene Hydrosilylation
(2015-11-30)
Chapter 1 describes tandem dual hydrosilylations of α,β-unsaturated enals. Hydrosilylations of both carbonyl compounds and alkenes have been utilized to create chiral alcohols. Tandem dual hydrosilylations (TDH) of ...