Browsing Library by Author "Johnson-Winters, Kayunta"
Now showing items 1-9 of 9
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ANTIOXIDATIVE AND ANTINEOPLASTIC EFFECTS OF Mn(III) SALPHENS, S-ALLYL CYSTEINE AND ITS SYNTHETIC ANALOGUES
Raghavan, Koushik (University of Texas at Arlington Libraries, 2015-12)Presently used chemotherapeutic drugs are not very selective and do not have the capability to differentiate between normal cells and malignant cells, which leads to the development of adverse side-effects and systemic ... -
Concomitant Studies Of Two F420 Cofactor Dependent Enzymes: Binding Isotherms Of F420 Cofactor Dependent Glucose-6-phosphate Dehydrogenase And Kinetic Analysis Of F420H2: NADP+ Oxidoreductase Utilizing Isotope Effects Methods
Du, SiqiF420 cofactor, a flavin analogue, is a unique two electron carrier that has been found in a number of microorganisms. This thesis focuses on two F420-dependent enzymes (F420-dependent glucose-6-phosphate dehydrogenase and ... -
F₄₂₀ cofactor dependent enzymes : kinetic, mechanistic and structural characterization of F₄₂₀-dependent glucose-6-phosphate dehydrogenase (FGD) from Mycobacterium tuberculosis
Oyugi, Mercy A; 0000-0002-2600-745X (2017-08-02)F₄₂₀-dependent glucose-6-phosphate dehydrogenase (FGD) from Mycobacterium tuberculosis (Mtb) is one of a few enzymes that utilize the unique F₄₂₀ cofactor for catalysis. FGD catalyzes the first committed step of the ... -
INCREASED HYDRIDE TRANSFER RATES WITHIN T09A MUTANT OF F420:H2 NADP+ OXIDOREDUCTASE
Ullah, Md Hasmat; 0000-0003-2839-4091 (2016-05-18)F420:H2 NADP+ oxidoreductase (Fno) is an F420 dependent enzyme found in methanogens and sulfate reducing archaea. Fno catalyzes the reversible reduction of NADP+ to NADPH through the transfer of a hydride involving F420 ... -
Investigation of F420-dependent glucose-6-phosphate dehydrogenase variants using pH profiles and stopped-flow spectrometric ligand-binding methods
Alvarez, Ana Laura; 0000-0002-9728-8113 (2022-05-18)**Please note that the full text is embargoed until 5/17/2024** ABSTRACT: F420-dependent glucose-6-phosphate dehydrogenase (FGD) from Mycobacteria tuberculosis, catalyzes a reaction the conversion of glucose-6-phosphate ... -
Mechanistic And Kinetic Studies On F420H2: NADP+ Oxidoreductase From Archeoglobus fulgidus
Le, Cuong QuangF420H2: NADP+ Oxidoreductase (Fno) is an F420 cofactor dependent enzyme that catalyzes the reversible reduction of NADP+ to NADPH by transferring a hydride from the reduced F420 cofactor. F420 cofactor is an essential ... -
MECHANISTIC STUDIES OF F420-DEPENDENT ENZYMES BY KINETIC ANALYSIS
Davis, Lindsay A (2021-08-10)The focus of this research is to elucidate the catalytic mechanism of F420-dependent enzymes using F420-dependent glucose-6-phosphate dehydrogenase (FGD) from Mycobacteria tuberculosis (Mtb) and F420H2:NADP+ Oxidoreductase ... -
Probing Inter-Subunit Communication of F₄₂₀ NADP Oxidoreductase: A Kinetic Analysis
Pugh, Denzel L; 0000-0002-7909-6206 (2019-05-20)F₄₂₀-dependent enzymes are important in a number of organisms, which play vital roles in methane production, NADPH regulation, nucleic acid biosynthesis, folate biosynthesis and carbon cycling. Until our recent publications ... -
Recombinant Expression, Purification And Kinetic Characterization Of F₄₂₀-cofactor Dependent Glucose-6-phosphate Dehydrogenase From Mycobacterium tuberculosis
Osumah, Tijani (Biomedical Engineering, 2013-07-22)The FGD (F₄₂₀-dependent Glucose-6-phosphate dehydrogenase) enzyme is an F₄₂₀ Cofactor (7,8-didemethyl-8-hydroxy-5-deazariboflavin) dependent enzyme found in Mycobacterium tuberculosis, the causative agent of tuberculosis ...