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Proposing a Sparse Weighted Directed Network Construction Method and a Novel Mutual-Information based Sparse Feature Selection Algorithm for Multivariate Time-series Analysis and its Application in Medical Diagnostic Problems
(2018-08-24)
The main purpose of this study is feature engineering/learning from multivariate (MV) time-series to achieve a more interpretable model by dimension reduction. This aim is fulfilled in 2 main parts. In part 1, we proposed ...
ONLINE BIOANALYTICAL MASS SPECTROMETRY METHODS FOR ANALYSIS OF SMALL AND LARGE BIOMOLECULES USING ONE- AND TWO-DIMENSIONAL LIQUID CHROMATOGRAPHY
(2018-12-06)
In recent years, the innovation in biomarkers and biotherapeutics has increased the demand for state-of-the-art analytical platforms to achieve reliable and accurate discoveries and quantitative analysis methods. The ...
NANOPORE BIOSENSORS FOR MOLECULAR DETECTION AND ANALYSIS
(2018-05-17)
Nanoscale fabrication techniques have led the march towards a new class of biosensors that were not possible to build in the past due to technological limitations. These molecular nanosensors can have biochemical, ...
UNDERSTANDING KEY GENETIC MUTATIONS AND MOLECULAR ALTERATIONS ON INCREASING MIGRATION, VIABILITY, DRUG RESISTANCE OF MALIGNANT BRAIN TUMOR IN CONFINEMENT
(2017-08-10)
There are more than 120 types of primary brain and central nervous system tumors that affect people of all ages. Glioblastoma multiforme (GBM), for example, is the most frequent type of brain cancers and also among the ...