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Fabrication and In Vitro Characterization of an Implant for the Detection of Metastatic Cancer Cells
(2018-08-03)
Greater than 90% of cancer related deaths are due to metastasis (Hayes & Wicha, 2011). Since current conventional techniques detect the disease by the time that it has become systemic, our lab has developed a hydrogel based ...
Towards the Fabrication of Bioresorbable Constructs with Customized Properties using Additive Manufacturing
(2017-12-08)
Additive Manufacturing (AM) has been employed to fabricate medical constructs for over two decades. This dissertation investigates the effects of AM process parameters on raster level geometric features and structural ...
Engineering Elastic and Functional Electrospun Nano-Fibers for Potential Heart Repair
(2022-08-17)
In the United States and around the world, cardiovascular disease (CVD) has been one of the main causes of death since 1921, responsible for approximately 1 in 4 deaths domestically. Myocardial infarction (MI), or commonly ...
APPLICATION OF TISSUE ENGINEERING TECHNIQUES FOR TREATING CARTILAGE INJURY AND DIAGNOSING CANCER METASTASIS
(2019-08-05)
This study focuses on the application of tissue engineering techniques for the diagnosis of cancer metastasis, cartilage regeneration, and modeling of lymph node metastasis.
Chapter 1 is an overview of tissue engineering ...
PROCESSING BETA-TRICALCIUM PHOSPHATE AND 45S5 BIOGLASS MIXTURES FOR OSTEOGENIC BONE TISSUE SCAFFOLDS
(2017-08-18)
A 30% 45S5 Bioglass and 70% -tricalcium phosphate ceramic mixture, which was previously shown to be osteogenic [1], was sintered and the process was investigated as a strengthening mechanism. Samples were sintered for dwell ...
AMORPHOUS SILICA BASED BIOMATERIALS FOR MUSCULOSKELETAL TISSUE REGENERATION APPLICATIONS
(2021-08-02)
Musculoskeletal (MSK) injury includes any injuries that affect the bones, muscles, ligaments, tendons, or nerves. Open bone fracture is one of the common types of MSK traumatic injuries which results in not only bone ...