Browsing Theses and Dissertations(library) by Author "Liao, Jun"
Now showing items 1-6 of 6
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3D Microstructural characterization of heart valve leaflets
Adebo, Ifejola (2023-06-30)Heart valve disease is common in the world today and understanding the anatomical linkages, collagen, and elastin microstructures between the various heart valves is important for developing effective treatments. Four heart ... -
A Comparative Biomechanical Investigation of Porcine Neonatal and Adult Left Ventricular Tissues
Eastep, Timothy R; 0009-0000-6936-1558 (2023-05-22)A current trend in cardiac muscle regeneration and repair is to recreate the biophysical and biomechanical environment of the neonatal hearts, which has been shown to promote cardiac regeneration. This translational need ... -
EFFECTS OF AGING ON MOUSE ROTATOR CUFF TENDON BIOMECHANICS
Patwardhan, Chinmay Sagar; 0000-0002-2871-6006 (2021-12-21)Rotator cuff tendon injuries and tear are caused by overuse, falling, or other accidents, and are often associated with old age. The severe injuries and tear can be debilitating and require nonsurgical treatment for partial ... -
Engineering Elastic and Functional Electrospun Nano-Fibers for Potential Heart Repair
Taylor, Alan Mark (2022-08-17)In the United States and around the world, cardiovascular disease (CVD) has been one of the main causes of death since 1921, responsible for approximately 1 in 4 deaths domestically. Myocardial infarction (MI), or commonly ... -
Nanoparticle-Mediated Controlled Myocardial Drug Delivery: A New Treatment for Hypertrophic Cardiomyopathy
McGrath Copeland, Michelle Katherine; 0000-0002-9650-4646 (2020-09-04)Hypertrophic cardiomyopathy (HCM) is a genetic disease of the sarcomere, resulting in overgrowth of the septum that separates the left and right ventricles. HCM can affect as many as 1/200 people, making it the most common ... -
PORCINE NEONATAL HEART EXTRACELLULAR MATRIX AS A REGENERATION PLATFORM
Perez, Karla; 0000-0002-3348-7121 (2021-08-16)Each year, an estimated 620,000 Americans have new heart attack and suffer from myocardial infarction (MI) that results in massive heart cell death and decrease in heart function. Various therapeutic strategies, such as ...