Browsing Theses and Dissertations(library) by Author "Peng, Yuan Bo"
Now showing items 1-20 of 20
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The Antinociceptive Role Of The Anterior Interposed Nucleus Of The Cerebellum
Hagains, Christopher E. (Psychology, 2013-03-20)The cerebellum has been extensively studied for its role in pain. It is safe to say that the cerebellum has a modulatory role in pain. It is active during various types of pain, but it also plays a role in inhibiting ... -
Assessing the Impact of Pain on Decision-making in a Rat Gambling Task (RGT)
Salcido, Celina Antionette; 0000-0003-2208-6047 (2017-07-31)Recent clinical assessments using the Iowa Gambling Task have revealed pain can negatively affect decision-making processes, leading to risky or poor decisions. Despite the gain these models have made in further elucidating ... -
BEHAVIORAL AND LOCAL FIELD POTENTIAL CHANGES IN THE THALAMUS AND ANTERIOR CINGULATE CORTEX OF BEHAVING RATS EXPERIENCING POST HERPETIC NEURALGIA
Strand, Jennifer (2016-11-30)Post herpetic neuralgia (PHN) is experienced as burning pain in the facial region, caused by nerve damage from the herpes zoster virus. The pain often becomes chronic and debilitating. Investigations into the pain pathway ... -
Competition Between Dorsal Root Reflex And Sympathetic Activity On Neurogenic Inflammation
Li, Ailing (Psychology, 2012-04-11)Neurogenic inflammation is caused by the inflammatory substances released from the peripheral terminals of afferent fibers. Vasodilation is one of the cardinal signs of neurogenic inflammation. It is thought that neurogenic ... -
The Contribution Of The Dorsal Root Reflex And The Sympathetic Nervous System In Formalin-evoked Neurogenic Inflammation
Kachlic, Lara A. (Psychology, 2008-09-17)The present study investigated the role of dorsal root reflex (DRR), which is characterized as antidromic firing via primary afferent fibers towards the periphery, and the sympathetic nervous system in neurogenic inflammation. ... -
The Effect Of Morphine On Dopamine Neuron Activation In Males And Cycling Females
Eimerbrink, Micah (Psychology, 2012-04-11)The aim of this study was to evaluate the influence of estrogen on the electrophysiological response of ventral tegmental area (VTA) dopamine (DA) neurons to morphine (10 mg/kg; IP) in experimentally naïve adult male and ... -
The Effect Of Pag Stimulation Evoked Dorsal Root Reflexes In Neurogenic Inflammation
Herath, Pushpani Menaka (Psychology, 2009-09-16)Neurogenic inflammation is defined as inflammation produced by the sensory nerves. It contributes to the cardinal signs of inflammation: rubor (redness), tumor (swelling), color (heat), and dolor (pain or itch). It suggested ... -
ELECTROPHYSIOLOGICAL ANALYSIS ASSESSING THE ANALGESIC NATURE OF THE LATERAL HABENULA (LHb)
Parchure, Akshay Sunil (2019-07-19)Local field potential (LFP) is a collective neural signal of all the synaptic activity occurring at a specific area of the brain, thereby offering a unique insight into how the brain functions. The habenula is involved in ... -
Evaluating the Impact of Age and Time on Sensory and Affective Levels of Pain Processing
Geltmeier, Maxine Kaylen; 0000-0001-8171-3595 (2018-11-30)The relationship between pain and age has been studied for decades. However, research has produced conflicting results for pain thresholds and pain affect in clinical assessments. Likewise, pre-clinical research is conflicting ... -
Fabrication and modification of implantable micro-probes for neuro-studies
Cao, Hung Viet (2014-09-17)In this work, different types of implantable probes fabricated on Si and polyimide substrates for sensing neurotransmitters, recording extracellular action potentials and stimulating the neurons have been developed. Several ... -
Investigating The Optical Signals In The Brain And Spinal Cord During Nociception
He, Ji Wei (Psychology, 2010-07-19)Neuroimaging technologies have been widely used to study brain functioning based on a tight correlation between neurons and neighboring vasculature during neural activation, called neurovascular coupling. However, many ... -
The Local Field Potential In The Medial Prefrontal Cortex In Respose To Peripheral Nerve Stimulation
Li, Ailing (Psychology, 2014-09-17)Nociceptive stimuli can activate peripheral nociceptors to produce nociceptive signals which can be projected to the spinal cord and further up to the thalamus and many other cortical and subcortical areas through ascending ... -
Local Field Potential Signatures In The Anterior Cingulate And Primary Somatosensory Cortices During Pain Processing
Harris Bozer, Amber Lee AnnPain is the primary motive to seek physician care and animal research is informative for investigating the brain activity that underlies pain. Extensively studied brain areas involved in pain processing include the anterior ... -
Multi-region Local Field Potential Signatures and Brain Coherence Alternations in Response to Migraine Attacks
Wang, Zhen (2022-05-09)Migraine is a recurrent primary headache disorder with moderate to severe disability. It has been ranked as the second leading cause of disability and the sixth most prevalent disease. However, the pathophysiology of ... -
Pain Modulation By The Amygdala: Hemispheric Lateralization Of Pro- And Anti-nociceptive Properties During The Progression Of Inflammatory Pain
Kajumba, Mayanja M.Inflammatory pain is a feature of various diseases, and a leading cause of disabling discomfort among patients. Despite the extensive and costly neurophysiological and pharmacological research, even the most potent of the ... -
Peripheral Blood Perfusion Induced By Electrical Stimulation Of The Anterior Cingulate Cortex
He, Ji Wei (Psychology, 2007-08-23)In the last decade, much research has implicated the anterior cingulate cortex (ACC) in the modulation of both emotion and visceral functions in primates and rats. Rat studies have shown that electrical stimulation of ... -
Septal Stimulation Inhibits Spinal Cord Dorsal Horn Neuronal Activity
Hagains, Christopher E. (Psychology, 2008-09-17)Deep Brain Stimulation is a useful technique for relieving chronic pain in patients that have exhausted their options. The septum has been a target for such treatment. The purpose of this study was to determine if ... -
Sex Differences in Balance Measures and Chronic Low Back Pain in Older Adults
Bevers, Kelley; 0000-0003-4303-748X (2018-06-21)The older adult population is growing at a rapid pace, with the US Census Bureau estimating older adults to comprise of 20% of the overall population by 2020. Now, more than ever, we must parse out differences within this ... -
SIMULTANEOUS MULTI-REGION LOCAL FIELD POTENTIAL RECORDINGS IN RESPONSE TO NOXIOUS STIMULI FROM FREELY MOVING RATS
Wang, Zhen (2019-12-06)Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage” can be ignited by noxious chemical (e.g. acid), mechanical (e.g. pressure) and ... -
THE PAIN IN THE PLEASURE: ELECTROPHYSIOLOGICAL ANALYSIS OF THE TAIL REGION OF THE VENTRAL TEGMENTAL AREA (tVTA)
Parchure, Akshay (2020-12-07)The mesolimbic (midbrain) reward system is well documented to be involved with the analgesic effects of opioids, which involves the ventral tegmental area (VTA) causing release of dopamine (DA). The dopamine neurons from ...