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PREPARATION OF DUAL FLUORESCENCE AGENTS-LOADED NANOPARTICLE AND ITS IN VITRO AND IN VIVO APPLICATION
(2018-12-07)
There’re many existing imaging tools that composed of different imaging moieties to improve both resolution and sensitivity, however there’s not yet any imaging method that could be effectively utilized in both in vitro ...
Development of Particle Platforms for Delivery of Angiogenic Reagents to Treat Peripheral Arterial Diseases
(2019-01-11)
Peripheral arterial disease (PAD) is a disease that one or several peripheral arteries are narrowed or blocked. PAD is an emerging disease that cost annually 10-20 billions of US dollars for health care in America. PAD ...
Study on Forming DNA-Mediated Nanoparticle Conjugates: Toward Detection of COVID-19
(2021-12-21)
The objective of this thesis is to establish a rapid, robust, and reproducible procedure to controllably assemble DNA-functionalized Au nanoparticles (AuNPs) into satellite-shaped nanostructures using sequence-specific DNA ...
Poly(lactic-co-glycolic acid) Nanoparticle Delivery of Notch Intracellular Domain Plasmid to Restore Notch Signaling
(2021-08-23)
Notch signaling is a highly conserved signaling system that is required for embryonic development and regeneration of organs. When the signal is lost, maldevelopment occurs and leads to a lethal state. Delivering exogenous ...