Browsing Department of Bioengineering by Title
Now showing items 299-318 of 338
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Study Of NIRS Based Motor Cortex Activation Patterns In Cerebral Palsy Affected Kids Using Image Based Metrics
(Biomedical Engineering, 2008-09-17)In recent years the National Institutes of Health has placed great emphasis on addressing the emergent need to accelerate translation of laboratory discoveries into clinical practice. The proposed study is very much aligned ... -
Study Of Normobaric Hyperoxia Effects During Focal Hypoxia-ischemic Injury In Mice Using Optical Spectroscopy Measurements
(Biomedical Engineering, 2008-09-17)Optical spectroscopy has seen tremendous growth and development in recent years and has been extensively used to characterize the optical properties of biological tissues. The purpose of this study is to investigate the ... -
A Study Of The Physiological Effects Of Sleep Apnea On Cerebral Blood Flow Velocity
(Biomedical Engineering, 2010-11-01)It is estimated that sleep apnea is prevalent in the US in about 18 million people. The prevalence rate is approximately 6% in the US. Sleep apnea reduces the quality of life of patients. Sleep apnea is characterized by ... -
STUDY OF UPREGULATION OF DRUG RESISTANCE IN H460 LUNG CANCER CELLS VIA MICROCHANNEL DEVICE
(2020-05-14)Metastasis is the main reason of high mortality rates in cancer patients. Treating these patients becomes difficult once the cancer has metastasized, especially due to their drug resistance. Drug resistance is a common ... -
A Study On The Effect Of Mechanical Stretch And Aligned Scaffold Architecture On Morphology Of Rat Ventricular Cells
(Biomedical Engineering, 2009-09-16)Heart disease is one of the major causes of death in developing and industrialized countries. Myocardial infarction leads to remodeling of the left ventricle, which severely affects the pumping efficiency of the heart. In ... -
Subcellular Light Activation, Control And Manipulation Using A Dynamically Reconfigurable Nanopatterning System
(Biomedical Engineering, 2008-09-17)Cellular communication is the basis of all cellular activities and functions. Cell signaling is crucial in the processes of tissue maintenance, tissue development and homeostasis. Errors in transmission or interpretation ... -
Substrate Stiffness Adjustable PDMS Device/array For Understanding Its Effect On Cell Growth, Differentiation And Migration
(Biomedical Engineering, 2011-10-11)The mechanical properties of the cellular environment play an important role in the functioning of the cell. Cells attach to the extracellular matrix or other surrounding cells, thus sensing their mechanical properties and ... -
Surface Modification Of Magnetic Nanoparticles For Formulation Of Photoluminescent Polymer-coated Magnetic Nanoparticles To Detect And Treat Cancers
(Biomedical Engineering, 2013-03-20)Cancer has been one of the leading causes of death worldwide that necessitates the development of theranostic systems for effective cancer management. Previously, we developed biodegradable-photoluminescent polymer coated ... -
Surgical Fluorescence Imager For Visualizing Anteriorly Placed Biliary Structures, In-vivo During Human Cholecystectomy
(Biomedical Engineering, 2008-09-17)Cholecystectomy is one of the most common procedures occurring in United States to cure gall bladder diseases. There are two means of performing this procedure, Open Cholecystectomy and Laparoscopic Cholecystectomy, the ... -
Synthesis And Characterisation Of Raman Nanotags For Molecular Detection
(Biomedical Engineering, 2009-09-16)The realization that most diseases are preceded or accompanied by changes in the genetic and cellular level of an organism has increased with the need for imaging modalities, with the sensitivity and specificity, to ... -
Synthesis And Characterization Of Crosslinked Urethane Doped Polyesters For Vascular Tissue Engineering
(Biomedical Engineering, 2009-09-16)Traditional crosslinked polyester elastomers are inherently weak, and the strategy of increasing crosslink density to improve their mechanical properties makes them brittle materials. Biodegradable polyurethanes, although ... -
T-CELL MEMBRANE CAMOUFLAGED NANOPARTICLES FOR TREATMENT OF MELANOMA
(2017-05-30)Melanoma is one of the most aggressive skin cancers. The American Cancer Society reports that every hour, one person dies from melanoma. While there are a number of treatments currently available for melanoma (e.g. surgery, ... -
Targeted Delivery Of Carbon Nanotubes To Cancer Cells
(Biomedical Engineering, 2010-07-19)CD22 is broadly expressed on human B cell lymphomas. Monoclonal anti-CD22 antibodies (MAbs) alone, or coupled to toxins, have been used to selectively target these tumors both in severe combined immunodeficient (SCID) mice ... -
Targeted Drug Delivery To Human Aortic Smooth Muscle Cells Using Biodegradable Nanoparticles
(Biomedical Engineering, 2008-09-17)Restenosis is a common problem that can occur in angioplasty patients. In order to reduce the restentosis rate, various treatments such as glucocorticoids and drug eluting stents have been used for angioplasty patients. ... -
TARGETED DRUG-LOADED NANOPARTICLE SYSTEM (TDNPS) TO AMELIORATE AND TREAT IDIOPATHIC LUNG FIBROSIS
(2022-12-19)Idiopathic pulmonary fibrosis (IPF) is a fatal progressive disease with a dismal prognosis and 3-5 years of survival. Up to date, there are no effective treatments, and a few current therapies that do not ameliorate the ... -
Targeted nanoparticles for cancer therapy: promises and challenge
(OMICS Group InternationalDepartment of Bioengineering, The University of Texas at Arlington, 2011) -
Targeting the Oligomannose Biomarker Present on Distinct Subsets of Non-Hodgkin Lymphomas
(2020-09-04)Subtypes of B cell non-Hodgkin’s lymphomas, including follicular lymphomas, have shown a unique high oligomannose presentation on their immunoglobulins that will interact with natural receptors of the innate immunity, ... -
TECHNIQUES TO IMPROVE ULTRASOUND-SWITCHABLE FLUORESCENCE IMAGING
(2017-08-14)Novel approaches to the improvement of ultrasound-switchable fluorescence (USF) imaging—a relatively new imaging modality that combines ultrasound and optical imaging techniques—have been proposed for early cancer detection. ... -
The Biomechanics of Cardiac Elastin and its Role in Bioengineering
(2020-09-09)Elastin is an essential structural protein responsible for the elasticity of many tissues, including skin, lungs, blood vessels, and other highly dynamic tissues and organs in the body. In the heart, cardiac elastin has ... -
The Hip-Spine Effect: How Pathological Femoro-Pelvic Interactions Contribute to Abnormal Lumbar Spine Loading
(2019-05-06)ABSTRACT THE HIP-SPINE EFFECT: HOW PATHOLOGICAL FEMORO-PELVIC INTERACTIONS CONTRIBUTE TO ABNORMAL LUMBAR SPINE LOADING Anthony Nicholas Khoury, Ph.D. The University of Texas at Arlington, 2019 Supervising Professor: Hal ...