Browsing Department of Bioengineering by Title
Now showing items 55-74 of 338
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Detection of Molecular Biomarkers involved in the Induction of EMT, migration and invasion, and drug resistance in breast cancer cells in 3D confinement
(2018-09-17)Standard-of-care regimes for cancer treatment have become more effective and sophisticated over the last decade due to research developments which facilitate specific targeting of treatments to certain cancers, and the ... -
Detection Of Positive Cancer Margins Intra-operatively During Nephrectomy And Prostatectomy Using Optical Reflectance Spectroscopy
(Biomedical Engineering, 2007-09-17)In recent years optical spectroscopies have become the basis for popular research activity directed towards the development of novel, noninvasive technologies for tissue diagnostics. The motivation for my research was to ... -
Detection Of Sleep Disordered Breathing Using Electroencephalography
(Biomedical Engineering, 2007-08-23)This study investigates the application of Electroencephalography (EEG) to detect Sleep disordered breathing (SDB) using power spectral analysis. A preliminary study was performed on 13 subjects (ages: 49.08 ± 8.82) ... -
Determining The Flow Characteristics Of A Perfusion Device For Donor Heart Transport
(Biomedical Engineering, 2008-08-08)Current technology has limits organ transport for transplantation to static storage, thereby reducing the reasonable distance of travel. Continuous machine perfusion has been proposed as a viable alternative to improving ... -
DEVELOPMENT AND INVESTIGATION OF FLUORESCENCE IMAGING PROBES
(2019-09-03)Fluorescence imaging has attracted much attention due to high sensitivity, spatial and temporal resolution, and fast acquisition time, for imaging biomolecular processes and for diagnosis of diseases such as cancer in early ... -
Development Of A Broadband Multi-channel NIRS System For Quantifying Absolute Concentrations Of Hemoglobin Derivatives And Reduced Scattering Coefficients
(Biomedical Engineering, 2008-08-08)Near infrared spectroscopy (NIRS) has been widely applied to investigate hemoglobin oxygenations of muscles, brain and breast tumors. Steady state reflectance techniques developed previously have been restricted to ... -
Development Of A Measurement System For Quantifying Ultrasound Field Distribution Of Different Transducers
(Biomedical Engineering, 2014-03-10)Ultrasound has been widely used in many fields, such as nondestructive examination and medical imaging. Ultrasound is mostly characterized by its pressure and, dynamic pressure wave can be considered to be the foundation ... -
Development Of A Model To Simulate The Single-limb Stance Phase Of Walking To Determine The Limits Of Stability
(Biomedical Engineering, 2013-07-22)Falls during walking are the primary cause of injuries for older persons and present a high associated cost to society due to the resulting treatment. Hence, the control of balance while moving is an essential issue ... -
Development Of A Multi-channel Handheld Probe Designed For Near Infrared Spectroscopy And An Exploration Into Its Clinical Applications
(Biomedical Engineering, 2007-08-23)Near Infrared (NIR) spectroscopy and imaging has become popular in research fields for the past 2 decades. My research focuses on the development of a handheld, multi-channel, multi-separation probe for the low-cost, ... -
Development of Algorithms to Analyze Electrogastrography (EGG) for Neonatal Gastrointestinal Development and Electroencephalography (EEG) for Effects of LED-based Pre-frontal Light Stimulation
(2022-05-17)Algorithm development, and biological signal processing are the key components for new applications of successful medical diagnosis that can provide physiological and functional information to better understand human ... -
DEVELOPMENT OF AN IN VITRO TBI MODELS AND VALIDATION OF NANODELIVERY FOR RESTORATION OF DISRUPTED BRAIN ENDOTHELIUM
(2019-09-06)Blast-induced traumatic brain injury (bTBI) is a serious concern among military personnel and their families. Although the mechanisms responsible for disruption to the brain are not well understood, the development of ... -
Development Of An In-vitro Assay For Neurotrophin-induced Segregation Of Nociceptive And Proprioceptive Sensory Axons
(Biomedical Engineering, 2007-08-23)Peripheral nerves have the capacity for regeneration and if properly repaired, axon extensions can regenerate even across gaps caused by peripheral nerve loss. Complete functional recovery after gap injury repair remains ... -
Development Of An Optical Spectroscopic Method To Detect Neurohemodynamic Changes Induced By Pain In Rats
(Biomedical Engineering, 2010-03-03)In my optical spectroscopy study, multi-channel, thin optical probes with short source-detector separation have been implemented, calibrated, and used along with a multi-channel spectrometer as a quantitative technique to ... -
Development Of Atlas-guided Diffuse Optical Tomography To Investigate Age-dependent Human Cognitive Functions Under Risk Decision Making
To better understand the age effect on neural correlates under risk decision-making stimulations, studies using advanced neuroimaging with a sufficient statistical power are desired. Diffuse optical tomography (DOT) of ... -
DEVELOPMENT OF CANCER TRAP FOR CAPTURING CANCER CELLS THAT METASTASIZE IN THE PERITONEAL CAVITY: A PRELIMINARY STUDY
(2017-05-25)Our laboratory has recently developed an implantable device - cancer trap that can recruit and trap circulating cancer cells inside the bloodstream. Since several types of cancer cells can metastasize inside the peritoneal ... -
Development Of Gelatin Microbubble Based PLGA Scaffold For Application In Bone Tissue Engineering
(Biomedical Engineering, 2013-03-20)The overall goal of the study was to develop a delivery system for a potential bone tissue engineering application focusing on fabrication of gelatin microbubble (MB) based PLGA scaffolds capable of recruiting Mesenchymal ... -
Development Of Magnetic-based Core-shell Nanoparticles For Drug Delivery Applications In Melanoma Skin Cancer
(Biomedical Engineering, 2010-11-01)Melanoma skin cancer is the most dangerous form of skin cancer and the major cause of deaths related to skin cancer worldwide. Conventional chemotherapeutic treatment is not very effective and faces many problems such as ... -
Development of Magnetic-based Multi-layer Microparticles For Stem Cell Isolation, Enrichment And Detachment
(Biomedical Engineering, 2013-03-20)Stem cells have been studied and used in several cell-based therapies for regenerative medicine, 3D tissue-engineered scaffolds, and in vitro models for drug screening and testing. For instance, cell based therapy via the ... -
Development of medical devices for diagnosing cartilage injury and metastatic cancers
(2019-08-07)My research focused on applying biomedical engineering techniques to diagnose different diseases and conditions. The results of these work led to one published paper and two submitted manuscripts which are summarized in ... -
Development of medical devices for osteoarthritis diagnosis, antimicrobial, wound closure, and wound pH milieu monitoring
(2019-12-10)Nanotechnology has been widely used in the field of biomedical engineering. For example, nanoparticles have been employed for targeted drug delivery due to their retention effect, increased permeability, site-specific ...