Browsing Department of Biology by Title
Now showing items 98-117 of 195
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Insights into the role and regulation of the mitochondrial unfolded protein response during pathogen infection
(2021-11-08)Mitochondria are essential cellular organelles known for their role in energy production, apoptosis, aging, calcium signaling and others. Due to their essential nature, mitochondria are often under attack by numerous ... -
Insights Into The Transmission Of Helitrons And Their Impact On The Genome Architecture Of Myotis Lucifugus, The Little Brown Bat
(Biology, 2011-03-03)Probably the most dynamic proportion of multicellular eukaryotic genomes is composed of teeming populations of parasitic mobile DNA, called transposable elements (TEs). Helitrons are rolling circle TEs that have a limited ... -
Integration Mechanism Of The Site Specific Non-LTR Retrotransposon, R2Bm
(Biology, 2010-07-19)The focus of this thesis is the mechanistic study of non-LTR retrotransposon replication using the site specific transposon R2Bm. Non-LTR retrotransposons integrate into new chromosomal sites by copying their RNA back ... -
The Interplay Of Environmental Stressors On The Life History Traits In Daphnia lumholtzi
(Biology, 2014-12)In natural environments, organisms face multiple stressors that threaten their persistence. Aquatic organisms respond to a change in environmental conditions by adaptively modifying the expression of traits (i.e., ... -
Intra-specific Variation Across A Small Temperature Difference In The Spider Rabidosa rabida (Araneae: Lycosidae) From The Mountains In Arkansas
(Biology, 2011-07-14)Temperature affects all levels of biological organization and ultimately affects multiple aspects of ecological performance and fitness. Generalist arthropod predators are ectothermic and are strongly affected by temperature ... -
INVESTIGATING GENE EXPRESSION CHANGES IN DAPHNIA: THE ROLE OF EMS-INDUCED MUTATIONS AND REPRODUCTIVE MODES
(2022-08-03)Gene expression variation is a common source of phenotypic variation between species. Understanding how changes in gene expression are associated with a particular phenotype will aid in understanding the molecular basis ... -
INVESTIGATING THE MICROEVOLUTIONARY PROCESSES THAT PROMOTE AND MAINTAIN BIODIVERSITY AND TRAIT NOVELTY
(2021-08-02)Gene flow, mutation, selection, and genetic drift influence patterns of speciation, adaptation, and biodiversity. In the age of genomics, we have been increasingly able to understand the interplay between these ... -
Investigation Of Potential Virulence Factors In Pathogenic Marine Bacteria
(Biology, 2014-09-17)Coral reefs provide numerous ecological and economic functions and are critical to biodiversity in marine environments. Critical to coral reef health and diversity is the microbial consortium within the coral host along ... -
Investigation of the Evolution and Structural Basis of Caspases: Insights into Conformational Dynamics, Stability and Allostery
(2023-05-01)Caspases, a class of cysteinyl proteases, are well known for their roles in apoptosis or programmed cell death. However, at lower levels of activation in the body, they also play other non-apoptotic roles in cell proliferation, ... -
Lack Of Respiratory Effects Of Nicotine Applied To The Caudal Medullary Raphé
(Biology, 2008-08-08)Breathing is an involuntary and automatic process initiated by a network of neurons within the brainstem. These neurons are affected by a number of factors (mechanical, electrical and chemical) that help modulate the ... -
Learning to Swim: An Exploration of the Terrestrial to Aquatic Transition in Elapids (Squamata: Elapidae)
(2021-12-20)Elapidae is an extremely diverse family of venomous snake that have a nearly global distribution. To conquer such wide swaths of territory the initially fossorial snakes evolved many successful strategies pertaining to ... -
LEVERAGING POPULATION GENOMICS ACROSS TWO TAXONOMICALLY DIVERSE NON-MODEL SYSTEMS TO UNDERSTAND PATTERNS OF DISEASE TRANSMISSION AND CONSEQUENCES OF HYBRIDIZATION
(2023-05-10)**Please note that the full text is embargoed until 05/10/2025** ABSTRACT: The field of population genomics has been mainly applied to questions centered around understanding molecular variation, impacts of evolutionary ... -
Leveraging the dynamic repeat element landscape of squamate reptile genomes to understand broad patterns of Vertebrate genome evolution and transposable element biology
(2019-11-20)Vertebrate genomes are mostly composed of transposable elements (TE), mobile DNA sequences that have shaped genome structure and evolution by promoting positive (e.g., regulatory network rewiring, embryo development) and ... -
Local And Watershed Influences On The Species Composition And Functional Organization Of Stream Diatom Communities In The Acid-impacted Adirondack Region Of New York
(Biology, 2014-03-12)For over 40 years, acid deposition has been recognized as a serious international environmental problem, but efforts to restore acidified streams and biota have had limited success. The need to better understand the effects ... -
Mechanisms Affecting Predation Success In Wolf Spiders
(Biology, 2014-09-17)Predator-prey interactions play a role in community structure through a variety of different mechanisms including direct consumption, density-mediated indirect effects, and trait-mediated indirect effects. Understanding ... -
MECHANISTIC BASIS FOR THE ROLE OF RESISTANCE AND TOLERANCE DETERMINANTS IN ANTIBIOTIC TREATMENT FAILURE
(2022-05-09)Failure of antibiotics in treatment of nosocomial Gram-negative bacterial infections has created a substantial burden for global public health. The β-lactam class of antibiotics includes last resort carbapenems, which are ... -
Mechanistic insights into Gram-negative envelope remodeling for protection against severe outer membrane defects
(2022-05-23)Gram-negative bacteria account for the majority of antibiotic resistant infections. Regulated modifications within the cell envelope can promote resistance to clinically important antibiotics. The increased prevalence of ... -
Microbial Diversity and Immunogenetics of Whiptail Lizards (Aspidoscelis)
(2022-08-10)Whiptail lizards of the genus Aspidoscelis are a complex of both sexual and asexual species with distributions in the United States, Mexico, and Central America. The parthenogenetic lineages arose through hybridization ... -
Modulation Of Innate Immunity In Arabidopsis
Plants possess a highly sophisticated defense system to fight against pathogen infection. One of the components of this system, stomatal immunity, was studied here. Stomata, formed by a pair of epidermal guard cells, are ... -
Molecular Mechanisms That Regulate the Stress Response In A. baumannii
(2023-08-14)**Please note that the full text is embargoed until 08/01/2025** Acinetobacter baumannii is particularly problematic in hospital settings, where infections can occur in a range of tissues. This bacterium can endure extreme ...