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dc.contributor.author | Nguyen, Kytai Truong | |
dc.contributor.author | Beck, Jonathan | |
dc.contributor.author | Angus, Ryan | |
dc.contributor.author | Madsen, Ben | |
dc.contributor.author | Britt, David | |
dc.contributor.author | Vernon, Brent | |
dc.date.accessioned | 2014-08-04T19:40:46Z | |
dc.date.available | 2014-08-04T19:40:46Z | |
dc.date.issued | 2007 | |
dc.identifier.citation | Published in TISSUE ENGINEERING Volume 13, Number 3, 2007 | en_US |
dc.identifier.issn | 1076-3279 | |
dc.identifier.other | ESSN: 1557-8690 | |
dc.identifier.uri | http://hdl.handle.net/10106/24522 | |
dc.description | This is a copy of an article published in the Tissue Engineering ©2007[copyright Mary Ann Liebert, Inc.]; Tissue Engineering is available online at: http://online.liebertpub.com. | en_US |
dc.description.abstract | **Please note that the full text is embargoed** ABSTRACT: Diabetes is one of the most prevalent, costly, and debilitating diseases in the world. Although traditional
insulin therapy has alleviated the short-term effects, long-term complications are ubiquitous and harmful.
For these reasons, alternative treatment options are being developed. This review investigates one appealing
area: cell replacement using encapsulated islets. Encapsulation materials, encapsulation methods,
and cell sources are presented and discussed. In addition, the major factors that currently limit cell
viability and functionality are reviewed, and strategies to overcome these limitations are examined. This
review is designed to introduce the reader to cell replacement therapy and cell and tissue encapsulation,
especially as it applies to diabetes. | en_US |
dc.description.sponsorship | Funding from an Undergraduate Research and Creative
Opportunities grant to Jonathan Beck and the Engineering
Initiatives at the Utah State University was used to support
the writing of this manuscript and work reported in it. We
would also like to acknowledge support from Fresenius
Medical Care, North America (Ben Madsen) and from NSFEEC
award #0431824 (David Britt, Kytai Nguyen). | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Mary Ann Liebert | en_US |
dc.subject | Diabetes | en_US |
dc.subject | Cell replacement | en_US |
dc.subject | Encapsulated islets | en_US |
dc.title | Islet encapsulation - Strategies to enhance islet cell functions | en_US |
dc.type | Article | en_US |
dc.publisher.department | Department of Bioengineering, The University of Texas at Arlington | en_US |
dc.identifier.doi | http://dx.doi.org/10.1089/ten.2006.0183 | |
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