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EVOLUTIONARY AND BIOCHEMICAL CHARACTERIZATION OF EFFECTOR CASPASES
(2021-04-16)
Caspases are an ancient class of cysteine-dependent aspartate-specific proteases that control apoptosis, responsible for cell differentiation, and maintain cellular homeostasis in multicellular organisms. Dysregulation of ...
Investigation of the Evolution and Structural Basis of Caspases: Insights into Conformational Dynamics, Stability and Allostery
(2023-05-01)
Caspases, a class of cysteinyl proteases, are well known for their roles in apoptosis or programmed cell death. However, at lower levels of activation in the body, they also play other non-apoptotic roles in cell proliferation, ...