Dissertations & Theses: Recent submissions
Now showing items 41-60 of 192
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MECHANISTIC BASIS FOR THE ROLE OF RESISTANCE AND TOLERANCE DETERMINANTS IN ANTIBIOTIC TREATMENT FAILURE
(2022-05-09)Failure of antibiotics in treatment of nosocomial Gram-negative bacterial infections has created a substantial burden for global public health. The β-lactam class of antibiotics includes last resort carbapenems, which are ... -
EFFECTS OF A N2-FIXING BIOFERTILIZER ON THE RHIZOSPHERE MICROBIOME AND THE INFLUENCE OF BIOCHAR ON SOIL FERTILITY AND MICROBIAL COMMUNITIES
(2021-12-20)The rhizosphere microbiota and endosymbionts are the major contributors to biogeochemical cycling and significantly impact the associated host plant. Their association with plant roots is inevitable for plant health and ... -
The Role of the Serine/Threonine Phosphatase PstP in the Mycobacterial Cell Wall Regulation
(2021-12-21)Mycobacterium tuberculosis (Mtb) is the causative agent of the deadly infection Tuberculosis (TB). The current standard antibiotic regimen for TB treatment combines fours drugs to be taken for at least six months. Mtb shows ... -
DEVELOPMENT OF NEW TECHNIQUES TO DISSECT THE GENETIC BASIS OF POPULATION-LEVEL VARIATION OF RECOMBINATION RATES IN THE DAPHNIA MODEL SYSTEM
(2021-12-20)We know very little about the determining genetic factors that control the recombination events within a genome. Moreover, the cause of recombination rate variation in population-level remains poorly understood, especially ... -
The Cellular and Genetic Mechanisms of Stress Response Pathways in Caribbean Coral
(2021-12-08)Reef-building corals are in decline around the globe due to both the effects of increased ocean temperatures and the emergence of marine diseases which affect corals. These emerging issues threaten the continued persistence ... -
Insights into the role and regulation of the mitochondrial unfolded protein response during pathogen infection
(2021-11-08)Mitochondria are essential cellular organelles known for their role in energy production, apoptosis, aging, calcium signaling and others. Due to their essential nature, mitochondria are often under attack by numerous ... -
Functional Analysis of Nuclear-Encoded Mitochondrial Gene Duplicates with Testis-Biased Expression in Drosophila melanogaster
(2019-08-12)Most of the genes encoding proteins that function in the mitochondria are located in the nucleus and are called nuclear-encoded mitochondrial genes (N-mt genes). In Drosophila melanogaster, most of the tissue-specific ... -
TWENTY YEARS OF LAND USE AND THE IMPACT OF NITRATE, E. COLI AND CHLOROPHYLL FOR TWO LAKES IN NORTH CENTRAL TEXAS
(2021-08-10)Clean and safe drinking water is a human right. Global, federal, and state agencies that monitor the source and quality of drinking water are limited in power and oversight. Historically, human groups have replaced wetland ... -
INVESTIGATING THE MICROEVOLUTIONARY PROCESSES THAT PROMOTE AND MAINTAIN BIODIVERSITY AND TRAIT NOVELTY
(2021-08-02)Gene flow, mutation, selection, and genetic drift influence patterns of speciation, adaptation, and biodiversity. In the age of genomics, we have been increasingly able to understand the interplay between these ... -
CHEMICAL AND GENETIC ANALYSIS OF THE MITOCHONDRIAL UNFOLDED PROTEIN RESPONSE
(2021-06-29)Mitochondria are essential for energy production, metabolic signaling, calcium homeostasis, and other roles. Consequently, mitochondrial dysfunction can result in cellular decline and the onset of disease. Cells use the ... -
UNCOVERING GENOMIC INSIGHTS TO THE DYNAMICS AND MECHANISMS OF SPECIATION USING LIALIS BURTONIS AND HETERONOTIA BINOEI
(2019-05-08)Species are fundamental entities in biology because their existence represents the cohesion that binds populations into a single unit. One facet of evolutionary biology is to identify the processes that cause the origin ... -
THE MECHANISM OF ENZYME STABILITY AND SPECIFICITY IN CASPASE-3
(2021-04-20)The caspase family has been found as regulated proteins that play an important role in apoptosis and inflammation. Incorrect caspase regulation may cause serious diseases such as cancer. Knowing the mechanisms and evolution ... -
Impacts of landscape and past climate on patterns of hybridization and genetic diversity in Plestiodon tetragrammus and P. multivirgatus
(2021-03-26)Past hybridization plays an important role in evolution of taxa. We use multiple phylogenetic approaches including single gene sequencing and high-through put sequencing to address the effects of past hybridization in the ... -
Leveraging the dynamic repeat element landscape of squamate reptile genomes to understand broad patterns of Vertebrate genome evolution and transposable element biology
(2019-11-20)Vertebrate genomes are mostly composed of transposable elements (TE), mobile DNA sequences that have shaped genome structure and evolution by promoting positive (e.g., regulatory network rewiring, embryo development) and ... -
The Food Habits and Feeding Behavior of New World Coral Snakes
(University of Texas at Arlington Libraries, 1973-05-01)This thesis considers the food habits and feeding behavior of New World venomous coral snakes, with emphasis on Micrurus fulvius a species that is found in the southeastern United States and northern Mexico. Literature records ... -
POPULATION GENOMICS AND CONSERVATION OF TEXAS CAVE AND SPRING SALAMANDERS (PLETHODONTIDAE: EURYCEA)
(2020-08-18)Understanding species boundaries and gene flow among the cave and spring salamanders of the central Texas region (genus Eurycea) has been a challenge for many decades. Although previous research has greatly increased our ... -
Stream Biodiversity and Co-occurrence Network Topology along Sub-continental to Global Nutrient and Land Use Gradients
(2020-07-21)Freshwaters are some of the most vulnerable ecosystems to global change forces, such as land use and eutrophication, implicated in the loss of biodiversity and biotic homogenization (increased similarity) of species ... -
Insertion Mechanism of Long Interspersed Elements (LINEs) and the role of the Linker Domain
(2018-08-27)Long Interspersed Elements (LINEs), also known as non-Long Terminal Repeat (non-LTR) retrotransposons are major group of transposable elements ubiquitous in eukaryotic genomes and are known to altogether influence the ... -
Domestication of PIF transposable elements transposases as regulatory proteins in Drosophila melanogaster
(2018-08-23)Transposable elements (TEs) are genetic units that are able to move and amplify within a host genome. As a result of their activities, TE insertions can cause disruptions of gene functions and ectopic recombination producing ... -
Toughing it out: understanding the interplay of phenotypic plasticity and evolution in stressful environments
(2019-08-05)Preserving the health of ecosystems on Earth rewards local communities with economic benefits and improved quality of life. Yet, humans often perform activities that disrupt natural systems and lead to declines in biodiversity ...