Browsing PhD Dissertations - DO NOT EDIT by Author "Boll, Joseph M"
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Investigation of the Evolution and Structural Basis of Caspases: Insights into Conformational Dynamics, Stability and Allostery
Joglekar, Isha; 0000-0001-7930-5533 (2023-05-01)Caspases, a class of cysteinyl proteases, are well known for their roles in apoptosis or programmed cell death. However, at lower levels of activation in the body, they also play other non-apoptotic roles in cell proliferation, ... -
Mechanistic insights into Gram-negative envelope remodeling for protection against severe outer membrane defects
Kang, Katie N; 0000-0003-3026-5360 (2022-05-23)Gram-negative bacteria account for the majority of antibiotic resistant infections. Regulated modifications within the cell envelope can promote resistance to clinically important antibiotics. The increased prevalence of ...