Browsing MS Theses - DO NOT EDIT by Title
Now showing items 29-48 of 188
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Decreased Expression Of Microtubules In Confined Microenvironments Leads To A Reduced Effect Of Paclitaxel On Breast Cancer Cells
(Biomedical Engineering, 2014-12)Despite the current medical options available to patients, cancer cells frequently remain after treatment and metastasize. This is particularly significant because secondary cancers account for 90% of cancer-related ... -
Design And Construction Of A Fast Spectrometer For Fourier Domain Optical Coherence Tomography
(Biomedical Engineering, 2007-08-23)A fast spectrometer capable of operating at 27.8 KHz is designed and calibrated to work in the wavelength range of 700-900 nm, to perform Fourier Domain Optical Coherence Tomography (FD-OCT). The OCT system is based on ... -
DESIGN AND DEVELOPMENT OF REAL-TIME SINGLE AND DUAL-WAVELENGTH DCS SYSTEMS TO STUDY SKELETAL MUSCLE BLOOD PERFUSION AND OXYGEN METABOLISM
The aim of this study was to utilize Diffused Correlation Spectroscopy (DCS) to design and develop real-time single and dual wavelength systems and assess the physiological impacts of exercises on blood perfusion. The study ... -
Design, Fabrication And Evaluation Of A Novel Microfluidic Based In Vitro Cell Migration Assay
(Biomedical Engineering, 2014-09-17)Microfabrication and microfluidic devices have been recognized as potential platforms for cell-based and drug screening studies. Human glioblastoma multiforme (hGBM) cells migrate inside the central nervous system (CNS) ... -
Detecting Clinical Biomarkers Using Diffusion Tensor Imaging
(Biomedical Engineering, 2012-07-25)Diffusion tensor imaging (DTI), a modality of MRI that measures water diffusion properties noninvasively, is highly sensitive to subtle structural changes of white matter. It provides a unique and noninvasive method for ... -
Detection Of Positive Cancer Margins Intra-operatively During Nephrectomy And Prostatectomy Using Optical Reflectance Spectroscopy
(Biomedical Engineering, 2007-09-17)In recent years optical spectroscopies have become the basis for popular research activity directed towards the development of novel, noninvasive technologies for tissue diagnostics. The motivation for my research was to ... -
Detection Of Sleep Disordered Breathing Using Electroencephalography
(Biomedical Engineering, 2007-08-23)This study investigates the application of Electroencephalography (EEG) to detect Sleep disordered breathing (SDB) using power spectral analysis. A preliminary study was performed on 13 subjects (ages: 49.08 ± 8.82) ... -
Determining The Flow Characteristics Of A Perfusion Device For Donor Heart Transport
(Biomedical Engineering, 2008-08-08)Current technology has limits organ transport for transplantation to static storage, thereby reducing the reasonable distance of travel. Continuous machine perfusion has been proposed as a viable alternative to improving ... -
Development Of A Measurement System For Quantifying Ultrasound Field Distribution Of Different Transducers
(Biomedical Engineering, 2014-03-10)Ultrasound has been widely used in many fields, such as nondestructive examination and medical imaging. Ultrasound is mostly characterized by its pressure and, dynamic pressure wave can be considered to be the foundation ... -
Development Of A Model To Simulate The Single-limb Stance Phase Of Walking To Determine The Limits Of Stability
(Biomedical Engineering, 2013-07-22)Falls during walking are the primary cause of injuries for older persons and present a high associated cost to society due to the resulting treatment. Hence, the control of balance while moving is an essential issue ... -
Development Of A Multi-channel Handheld Probe Designed For Near Infrared Spectroscopy And An Exploration Into Its Clinical Applications
(Biomedical Engineering, 2007-08-23)Near Infrared (NIR) spectroscopy and imaging has become popular in research fields for the past 2 decades. My research focuses on the development of a handheld, multi-channel, multi-separation probe for the low-cost, ... -
Development Of An In-vitro Assay For Neurotrophin-induced Segregation Of Nociceptive And Proprioceptive Sensory Axons
(Biomedical Engineering, 2007-08-23)Peripheral nerves have the capacity for regeneration and if properly repaired, axon extensions can regenerate even across gaps caused by peripheral nerve loss. Complete functional recovery after gap injury repair remains ... -
Development Of An Optical Spectroscopic Method To Detect Neurohemodynamic Changes Induced By Pain In Rats
(Biomedical Engineering, 2010-03-03)In my optical spectroscopy study, multi-channel, thin optical probes with short source-detector separation have been implemented, calibrated, and used along with a multi-channel spectrometer as a quantitative technique to ... -
DEVELOPMENT OF CANCER TRAP FOR CAPTURING CANCER CELLS THAT METASTASIZE IN THE PERITONEAL CAVITY: A PRELIMINARY STUDY
(2017-05-25)Our laboratory has recently developed an implantable device - cancer trap that can recruit and trap circulating cancer cells inside the bloodstream. Since several types of cancer cells can metastasize inside the peritoneal ... -
Development Of Gelatin Microbubble Based PLGA Scaffold For Application In Bone Tissue Engineering
(Biomedical Engineering, 2013-03-20)The overall goal of the study was to develop a delivery system for a potential bone tissue engineering application focusing on fabrication of gelatin microbubble (MB) based PLGA scaffolds capable of recruiting Mesenchymal ... -
Development Of Magnetic-based Core-shell Nanoparticles For Drug Delivery Applications In Melanoma Skin Cancer
(Biomedical Engineering, 2010-11-01)Melanoma skin cancer is the most dangerous form of skin cancer and the major cause of deaths related to skin cancer worldwide. Conventional chemotherapeutic treatment is not very effective and faces many problems such as ... -
Development of Magnetic-based Multi-layer Microparticles For Stem Cell Isolation, Enrichment And Detachment
(Biomedical Engineering, 2013-03-20)Stem cells have been studied and used in several cell-based therapies for regenerative medicine, 3D tissue-engineered scaffolds, and in vitro models for drug screening and testing. For instance, cell based therapy via the ... -
Development Of Microscope Stage Incubator For Long-term Monitoring Of Neuronal Cell Culture During Axotomy
(Biomedical Engineering, 2010-03-03)It is imperative to understand the patterns in regeneration of the central and peripheral nervous system after injury. This understanding would provide a fundamental cue towards molecules and other factors involved in ... -
Development Of Novel Multilayered Particles For Drug Delivery And Cell Isolation Applications
(Biomedical Engineering, 2011-03-03)The objective of this work is to develop multilayered nanoparticles for drug delivery and cell isolation applications. These particles principally consist of three layers; biodegradable polymer, thermo sensitive polymer ... -
Development Of Targeting Nanoparticles Mimicking The Adhesive Properties Of Platelets
(Biomedical Engineering, 2007-08-23)The development of biodegradable nanoparticles as drug delivery vehicles presents an improved avenue for intracellular targeted drug delivery. Biodegradable nanoparticles have demonstrated an ability to provide controllable, ...