Browsing Dissertations & Theses by Title
Now showing items 22-40 of 40
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LEFT ATRIAL FUNCTION ACROSS THE HEART FAILURE CONTINUUM: NOVEL PATHOPHYSIOLOGIC INSIGHT INTO DIASTOLIC DYSFUNCTION IN WOMEN WITH ISCHEMIA BUT NO OBSTRUCTIVE CORONARY ARTERY DISEASE
(2019-06-04)Women with signs and symptoms of ischemia but no obstructive coronary artery disease (INOCA) are at increased risk of developing heart failure with preserved ejection fraction (HFpEF); however, the exact mechanism for HFpEF ... -
Novel Mechanisms of Peripheral Vascular Dysfunction in Patients with Type 2 Diabetes
(2020-08-04)Currently, over 30 million adults in the United States have been diagnosed with Type 2 Diabetes mellitus (T2D). Importantly, T2D disproportionately augments the risk for the development of cardiovascular disease (CVD), ... -
Partitioning the Role of Myocardial Steatosis on Left Ventricular Function
(2023-08-07)**Please note that the full text is embargoed until 8/1/2025** ABSTRACT: Preclinical studies have long suggested that excess lipid accumulation within cardiomyocytes (myocardial steatosis) leads to adverse cardiac remodeling ... -
Pathophysiology of Exercise Intolerance in Breast Cancer Survivors Treated with Anthracycline Chemotherapy
(2019-12-02)Anthracyclines emerged as frontline breast cancer adjuvant therapy in the late 1960’s. Within half a decade of their clinical adoption, dose-limiting cardiotoxicity was recognized and cumulative dose limits were established ... -
Racial Disparities in Vascular Function:The Role of Oxidative Stress
(2018-05-04)Hypertension disproportionately affects the black population, contributing to a greater impact of cardiovascular disease in these individuals. While multiple factors underlie the development of hypertension in this population, ... -
Racial Disparity in Cardiovascular Disease and Oxidative Stress in African American Women
(2018-08-10)ABSTRACT Several studies have demonstrated that African Americans (AA) exhibit elevations in systemic oxidative stress compared to Caucasian Americans (CA). Peripheral blood mononuclear cells (PBMCs) have been identified ... -
Reducing Disparities in Physical Activity and Early Child Development: A Systematic and Observational Approach
(2022-08-15)**Please note that the full text is embargoed until 8/14/2024** ABSTRACT: Engaging in adequate (180 minutes per day) physical activity (PA) is an important component in positioning a young child towards optimal health. PA ... -
SEX DIFFERENCES AND VASCULAR MECHANISMS OF ELEVATED CARDIOVASCULAR DISEASE RISK IN NON-HISPANIC BLACK INDIVIDUALS
(2021-08-05)Cardiovascular diseases (CVD), including hypertension, disproportionately affect the non-Hispanic black (BL) population in the United States. Despite being an inherently multifactorial process, altered vascular function ... -
SHORT-TERM INTERMITTENT PARATHYROID HORMONE 1-34 ADMINISTRATION AND BONE VASCULAR ALTERATIONS IN C57BL/6 MICE
(2018-08-06)Advancing age is associated with progressive bone loss, declines in vasodilator capacity of blood vessels, vascular rarefaction and bone marrow blood vessel ossification. Intermittent parathyroid hormone (PTH) administration ... -
Skeletal Muscle Oxidative Capacity in the Elderly
(2018-05-04)Age is the greatest risk factor for chronic disease and is associated with a marked decline in functional capacity and quality of life, with loss of skeletal muscle function regarded as a key contributing factor. While the ... -
Sympathetic Control of Blood Pressure in Young non-Hispanic Black Women
(2023-05-19)**Please note that the full text is embargoed until 05/15/2025** ABSTRACT: Non-Hispanic Black women in the United States have a greater prevalence of hypertension compared to non-Hispanic White women, which contributes to ... -
The acute effects of a rotational medicine ball throw exercise on baseball pitching biomechanics
(2019-06-03)The ability to throw at higher velocities with proper mechanics is very advantageous for baseball pitchers to increase performance and decrease injury risk. Pitching utilizes the movement of energy through the kinetic ... -
The Effect of Acute High Phosphate Intake on Muscle Metaboreflex Activation and Vascular Function
(2018-05-04)Emerging evidence suggests that long term high consumption of inorganic phosphate (Pi) is associated with an increased risk of cardiovascular disease. Importantly, with the growing abundance of processed foods, dietary ... -
The effect of midsole cushioning on the kinetics, kinematics, and control of running
(2018-08-03)The incidence of musculoskeletal injuries associated with the stress of running, known as running-related injuries (RRIs), has risen in conjunction with the resurgence of running as a health-related physical activity ... -
The Effects of Knee Joint Loading on Dynamic Tasks in Individuals Several Years Post-ACL Reconstruction
(2020-06-01)Joint loading of the lower extremity is studied to identify risk factors for anterior cruciate ligament (ACL) injuries and to determine limb asymmetries. Asymmetrical loading in the lower extremity during ACL reconstruction ... -
THE ROLE OF MUSCLE DAMAGE ON JOINT TISSUE
(2022-12-19)The musculoskeletal system is a highly diverse network of tissue that operates in conjunction to one other, both mechanically and biochemically. In states of disorder such as musculoskeletal disorders, this cross-communication ... -
Trunk Function in Manual Wheelchair Users in Static and Dynamic Conditions
(2020-06-04)The relationship between functional capacity and trunk control is of significant interest to a variety of people, from wheelchair sport clinicians and professionals to rehab specialists, but has proven difficult to quantify. ... -
Understanding Components of Motor Imagery Ability and the Association with Motor Proficiency in Children and Young Adults
(2020-07-13)Motor imagery (MI) refers to the imagination of a motor task without actual movement execution (Decety & Grézes, 2006) and is believed to represent one’s ability to accurately utilize forward internal models of motor control ... -
Whole Body Vibration as an Innovative Intervention to Improve Physical Function and Vascular Health within a Lifespan
(2019-09-06)Over the past several decades, technological advances in computers, transportation devices, and other automated devices have decreased the need for human locomotion and physical activity in the workplace and at home. The ...