Browsing Samir Iqbal, Ph.D. by Subject "Molecular biophysics"
Now showing items 1-2 of 2
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Electrical detection of single-base DNA mutation using functionalized nanoparticles
(Copyright American Physical Society,Department of Electrical Engineering, The University of Texas at Arlington, 2009-08-17)We report an electrical scheme to detect specific DNA. Engineered hairpin probe DNA are immobilized on a silicon chip between gold nanoelectrodes. Hybridization of target DNA to the hairpin melts the stem nucleotides. Gold ... -
A mesoscale model of DNA interaction with functionalized nanopore
(Copyright American Physical Society,Department of Electrical Engineering, The University of Texas at Arlington, 2009-11-30)Functionalized nanopores have been used recently for the detection of specific DNA. The interactions between the DNA and the nanopore are not well understood due to the small size of DNA/nanopore and dynamic translocation ...