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Supercharging and Multiple Reaction Monitoring Optimization of High Molecular Weight Intact Proteins using Triple Quadrupole Mass Spectrometry
(2019-07-17)
Various supercharging agents, such as meta-nitrobenzyl alcohol, dimethyl sulfoxide, trifluoroethanol (TFE), and sulfolane were tested in different concentrations to study the effects of supercharging agents on the charge ...
Probing Inter-Subunit Communication of F₄₂₀ NADP Oxidoreductase: A Kinetic Analysis
(2019-05-20)
F₄₂₀-dependent enzymes are important in a number of organisms, which play vital roles in methane production, NADPH regulation, nucleic acid biosynthesis, folate biosynthesis and carbon cycling. Until our recent publications ...
The Effects of the Stereochemistry of Ruthenium (II) Polypyridyl Complexes on Microtubules as Targets for Chemotherapy
(2019-05-16)
Ruthenium polypyridyl complexes (RPCs) are promising anticancer agents due to their robustness and tunability of their polypyridyl ligands. Their axial chirality generally allows for more selective binding to biological ...
Synthesis of modified polydiacetylene (PDA) polymers for the detection of infective species
(2019-08-09)
Polydiacetylene (PDAs) polymers are receiving more attention as biosensors due to their ability to change absorption and fluorescence properties upon sensing various chemical and physical changes in the environment. In ...
N-HETEROCYCLIC CARBENE AND BIS(PYRAZOLYL)METHANE SUPPORTED COPPER(I) AND SILVER(I) COMPLEXES OF ORGANOTRIFLUOROBORATES
(2019-05-23)
Organotrifluoroborates have gone from capturing the imagination of the scientific community to being used extensively in a host of applications ranging from being employed to study boron intermediates to being used as a ...