Browsing PhD Dissertations - DO NOT EDIT by Title
Now showing items 11-30 of 132
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Cell division in Mycobacteria: the role of SepIVA
(2023-05-11)Today, about a quarter of the world’s population are infected with Mycobacterium tuberculosis (Mtb) and therefore, are at risk of developing tuberculosis (TB) disease. Tuberculosis, on average, takes about six months to ... -
Characterization Of Anti-rotavirus Activities Of Saponin Extracts From Quillaja Saponaria
(Biology, 2010-11-01)Rotavirus is the leading cause of severe diarrhea disease in newborns and young children worldwide, estimated to be responsible for over 500,000 adolescent deaths mostly in developing countries each year. Rotavirus-related ... -
CHEMICAL AND GENETIC ANALYSIS OF THE MITOCHONDRIAL UNFOLDED PROTEIN RESPONSE
(2021-06-29)Mitochondria are essential for energy production, metabolic signaling, calcium homeostasis, and other roles. Consequently, mitochondrial dysfunction can result in cellular decline and the onset of disease. Cells use the ... -
Circadian Orchestration of Symbiotic Genes in Photosynthetic Nitrogen-Fixing Bacteria
(2018-05-04)Rhizobia have long been known for their symbiotic association with the roots of legumes where they perform nitrogen fixation in specialized organs called nodules. The photosynthetic strains of Bradyrhizobia are of particular ... -
Combating Bacterial Infections with In-Situ Detection and Antibiotic Technology
(2020-08-10)Currently, there is a looming crisis in the field of antibacterial drug therapy. The emergence of antibacterial drug resistance because of poor antibacterial stewardship, coupled with booming elderly populations, economic ... -
A Comparative Approach To Elucidating The Physiological Response In Symbiodinium To Changes In Temperature
(Biology, 2014-03-10)Coral reefs are one of the most biodiverse ecosystems, and play a large role in the functioning of oceanic and coastal ecosystems. They are currently declining around the world, largely due to the effects of climate change ... -
Comparative Thermal Biology And Associated Niche Differentiation Among the Five-Lined Skinks
(Biology, 2008-09-17)Three species of five-lined skinks (Plestiodon fasciatus, P. laticeps, and P. inexpectatus) occur in regional sympatry across much of the Southeastern United States. These closely-related species, at one or more levels of ... -
Comparison Of The DNA Methylation Patterns Between Interspecific Xenopus F1 Hybrids And Their Parental Species
(Biology, 2011-07-14)In this study the main focus is to compare the methylation patterns of interspecific Xenopus F1 hybrids to the parental species using Methyl-Sensitive Amplification Polymorphisms (MSAPs). Genomic DNA was extracted from the ... -
Comparison Of The Ingestion And Digestion Rates Of Ochromonas danica Grazing On Pseudomonas fluorescens Of Varying Food Quality
(Biology, 2007-08-23)Flagellate prey selection appears to depend on morphological characteristics of prey such as cell size and motility, as well as on physiochemical characteristics such as digestibility and cell surface characteristics. ... -
Completion of RLE LINE Integration Involves an Open "4-Way" Branched DNA Intermediate
(2020-05-29)Long Interspersed Elements (LINEs), also known as non-LTR retrotransposons, encode a multifunctional protein that reverse transcribes its mRNA into DNA at the site of insertion by target primed reverse transcription. The ... -
The Control Of Gene Expression By High Light Stress In Cyanobacteria Through The Apparent Two-component NblS-RpaB Signal Transduction Pair
(Biology, 2008-09-17)In nature photosynthetic organisms including cyanobacteria are dependent upon their ability to acclimate to changes in environmental conditions including light and nutrient levels. The NblS sensor kinase of the cyanobacterium ... -
DETERMINING HOW ANTHROPOGENIC CHANGE FILTERS BIOLOGICAL COMMUNITIES AND HOW SPECIES MODIFY THEIR TRAITS IN RESPONSE TO URBANIZATION
(2023-08-11)Humans are significantly altering the environment at an alarming pace, leading to a reduction in species diversity. This transformation has created modified habitats where some species struggle to survive, while a few ... -
DEVELOPING APPROACHES THAT LEVERAGE NEXT GENERATION SEQUENCING TO STUDY BROAD BIOLOGICAL PROBLEMS
(2019-11-18)The advent of Next Generation Sequencing has been an extremely powerful tool in transforming the way we answer biological questions today. With the price per base pair continuously decreasing, and throughput, sequencing ... -
Development and characterization of novel a TCRm antibody and its application as an immune checkpoint blocker
(2021-12-21)Immunotherapy, the treatment of diseases via targeted immune system activation, has recently shown extraordinary success in clinical trials for multiple malignancies. In contrast to a routine therapeutic regimen for cancer, ... -
DEVELOPMENT OF NEW TECHNIQUES TO DISSECT THE GENETIC BASIS OF POPULATION-LEVEL VARIATION OF RECOMBINATION RATES IN THE DAPHNIA MODEL SYSTEM
(2021-12-20)We know very little about the determining genetic factors that control the recombination events within a genome. Moreover, the cause of recombination rate variation in population-level remains poorly understood, especially ... -
Disease in a Changing Ocean: Ecoimmunological Approaches to Coral Reef Ecology
(2018-04-26)Increasing prevalence of anthropogenic stressors and climate change have resulted in rapid increases in the incidence and severity marine disease affecting a number of vulnerable taxa. Cnidarians, including both reef-building ... -
DIVERSIFICATION ON CONTINENTS AND ISLANDS: A HERPETOLOGICAL PERSPECTIVE
This dissertation seeks to understand the geological and climatological processes that have promoted diversification on continental and island systems. Using molecular genetic data generated using Sanger sequencing and ... -
Diversity And Community Organization In The Periphyton Of Recirculating Streams Channels Are Defined By Current Velocity And Nutrient Supply
(Biology, 2010-03-03)In a series of experiments taking place in recirculating artificial stream channels, periphyton communities growing on ceramic tiles were subjected to variations in current velocity and nutrient supply. The first experiment ... -
Diversity of the Fanged-Frog Complex, Limnonectes kuhlii (Anura: Dicroglossidae) on the Mountainous Regions of Java and Sumatra, Indonesia
(2021-12-21)The cryptic species complex, Limnonectes kuhlii, previously was considered to have a large range across Southeast Asia. Recent works have started to identify species within the complex using primarily genetic methodologies. ... -
Domestication of PIF transposable elements transposases as regulatory proteins in Drosophila melanogaster
(2018-08-23)Transposable elements (TEs) are genetic units that are able to move and amplify within a host genome. As a result of their activities, TE insertions can cause disruptions of gene functions and ectopic recombination producing ...