Browsing Dissertations & Theses by Title
Now showing items 120-139 of 301
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Hemodynamic Responses to Thermal Stimulation in the Prefrontal Cortex of the Brain measured by FNIRS
Although FMRI has marked its importance in the neurological research by understanding the brain activities, FNIRS has also set a new standard in the brain imaging study research with non-invasive and easy to use technology. ... -
High Precision Spatial And Temporal Control Of Neural Circuitry Using Semi-automated, Multiwavelength Nanopatterning System
(Biomedical Engineering, 2009-09-16)The ideal way to manipulate neurons would be to reversibly activate and inactivate neuronal firing and thus enable a bi-directional control. Many attempts have been made in the past to have such a tool. The traditional ... -
High Resolution Optical Coherence Tomography (OCT) System For Integration With A Multimodal Optical Imaging Workstation
(Biomedical Engineering, 2007-08-23)Development and construction of a high resolution Optical Coherence Tomography (OCT) system is described. OCT is one of the modalities in an integrated multimode optical imaging workstation built around an inverted ... -
IMPACT OF MUSCULAR FATIGUE AND ITS MODULATION USING TRANSCRANIAL PHOTOBIOMODULATION (tPBM) ON THE HUMAN BRAIN MEASURED BY FUNCTIONAL NEAR-INFRARED SPECTROSCOPY (fNIRS)
(2020-07-22)When performing exercise, the brain must register and simultaneously integrate input from feedforward (i.e., central command) and feedback (e.g., exercise pressor reflex) neural mechanisms to make appropriate cardiovascular ... -
Implantable Drug Delivery System With In-plane Micropump
(Biomedical Engineering, 2007-08-23)A MEMS based Implantable Drug Delivery System (IDDS) is discussed. The heart of the system is an in-plane MEMS micropump enables us to make a compact, inexpensive system. A conceptual IDDS design is proposed. This design ... -
Implementation of a pain generator controlled by pressure and feasability in its applications for functional near-infrared spectroscopy
(Biomedical Engineering, 2011-10-11)Pain is a sensory and emotional experience as a result of possible or definite tissue damage. The level of pain is subjective to the individual's consciousness of sensory stimuli. Pain stimuli can be noxious (i.e., ... -
In Situ Crosslinkable Polyesters For Tissue Engineering And Drug Delivery
(Biomedical Engineering, 2009-09-16)In situ crosslinkable elastic materials are increasingly being explored for various biomedical applications such as drug delivery and tissue engineering due to their site specific nature. The creation of an in situ ... -
In Vivo Tracking Of Mesenchymal Stem Cell Recruitment To Tissue Scaffolds
(Biomedical Engineering, 2010-07-19)The term "Stem cells" has been extensively used to describe precursor undifferentiated cells that have the capacity to self-renew and can also give rise to multiple tissue types. Many studies have been shown improved ... -
In vivo ultrasound-switchable fluorescence imaging and its applications
(2020-08-17)The conventional fluorescence imaging has limited spatial resolution in centimeters-deep tissue because of the tissue’s high scattering property. Ultrasound-switchable fluorescence (USF) imaging, a new imaging technique, ... -
Incorporation Of Vascular Endothelial Growth Factor And Pleiotrophin Into A Multiluminal Biosynthetic Nerve Implant For The Repair Of Peripheral Nerve Long Gap Defects
(Biomedical Engineering, 2011-03-03)To repair a fully transected nerve without putting undue tension on the nerve stumps, and too circumvent many of the obvious problems of using harvested nerve grafts synthetic nerve guides have been used in the clinical ... -
Influence Of Hypoxia, Hypercapnia And Inspiratory Efforts On Sympathoexcitation During Apnea
(Biomedical Engineering, 2008-09-17)Obstructive Sleep Apnea (OSA) is characterized by frequent periods of apnea resulting in hypoxia, hypercapnia and fluctuations of intrathoracic pressure (inspiratory efforts). Hypoxia, hypercapnia and inspiratory efforts ... -
Influence Of Polymer Surface Chemistry On The Recruitment Of Stem Cells In Mice
(Biomedical Engineering, 2008-08-08)The most troublesome biological response to the implantation of bloodcontacting biomaterials is inflammation, which thereby-sets in motion a cascade of adverse host responses. If devices for therapy and drug delivery could ... -
Innovations In ¹H MR Tissue Oximetry: New Probes And Pulses
(Biomedical Engineering, 2011-03-03)Low oxygenation level (hypoxia) of tissue leads to cellular dysfunction, damage and poor response to therapy. Quantitative measurement of tissue oxygenation is critical not only for the study of tissue physiology, but ... -
Integration Of Hyperspectral Imaging System For Optimized Data Acquisition And Control To Revolutionized Pathology Applications
(Biomedical Engineering, 2009-09-16)Detecting and measuring the interactions and expression levels of tumor markers in a cancerous cell are quintessential in prognosis and management of cancer. These have propagated the need to develop better microscopic ... -
Interactive Analytical Tool for Quantitative Corneal Confocal Imaging in vivo
(2016-05-19)The objective of this study was to develop an interactive software application for image reconstruction and analysis of the corneal data from an in vivo confocal microscope (Heidelberg Retinal Tomograph with Rostock Corneal ... -
INTUITIVE HUMAN ROBOT INTERFACES FOR UPPER LIMB PROSTHETICS
(2016-08-19)Modern robotic prosthetic devices for upper limb amputees promise to alleviate an important disability, but are underutilized due to the inability to properly control them. Specifically, the devices afford more degrees of ... -
INVESTIGATING CAUSAL INTERACTIONS IN THE HUMAN BRAIN USING EEG AND fNIRS
(2016-08-24)It is necessary for distributed neural assemblies to work in collaboration to achieve the most elementary brain functions. Activities within segregated neural assemblies are integrated to process an incredibly diverse ... -
Investigation of 1064-nm laser fluence within tissue phantoms and its in vivo effects on human brain networks
(2018-05-22)For the past few decades there has been an increasing interest in the usage of near infrared (NIR) laser in the medical optics field. This is due to a number of studies conducted on different animal models utilizing NIR ... -
Investigation Of Brain Activities Using Two State-of-the-art Diffuse Optical Imagers
(Biomedical Engineering, 2007-09-17)Near-Infrared Spectroscopy (NIRS) and diffuse optical imaging (DOI) are increasingly used to detect hemodynamic changes in the cerebral cortex induced by brain activity. The new commercially available DOI systems CW5 and ... -
Investigation Of Brain Activity In Prefrontal Cortex Under Noxious Pain Stimuli And During Psychological Test Using Functional Near Infrared Spectroscopy
(Biomedical Engineering, 2011-07-14)Functional Near Infrared Spectroscopy (fNIRS) is a non-invasive functional neuroimaging technique, which measures changes in oxy-hemoglobin (HbO) and deoxy-hemoglobin (HbR) concentrations based on the principle of near ...