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Microheater platform for selective detachment of DNA
(American Institute of Physics;, 2012-08-30)
Despite deoxyribonucleic acid (DNA)’s well-known temperature sensitivity, not much work has been reported on leveraging temperature to manipulate the interaction of DNA with surfaces. This paper describes a microheater ...
Electrical detection of single-base DNA mutation using functionalized nanoparticles
(Copyright American Physical Society,, 2009-08-17)
We report an electrical scheme to detect specific DNA. Engineered hairpin probe DNA are immobilized on a silicon chip between gold nanoelectrodes. Hybridization of target DNA to the hairpin melts the stem nucleotides. Gold ...
A mesoscale model of DNA interaction with functionalized nanopore
(Copyright American Physical Society,, 2009-11-30)
Functionalized nanopores have been used recently for the detection of specific DNA. The
interactions between the DNA and the nanopore are not well understood due to the small size of
DNA/nanopore and dynamic translocation ...
Direct current electrical characterization of ds-DNA in nanogap junctions
(Copyright American Institute of Physics;, 2005-04-05)
Measurements of DNA conductivity, hybridization, and melting using electronic means can have wide applications in molecular electronics and biological sensors. We have fabricated nanogap break-junctions by electromigration ...