Browsing Department of Chemistry and Biochemistry by Title
Now showing items 192-211 of 247
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Strategies for enhancing chromatographic efficiencies in chiral and achiral supercritical and liquid chromatography
(2020-09-01)The fundamental aim of chromatography has been to achieve baseline separation between the components of a mixture in the shortest possible time. Recently there has been a shift in the chromatographic focus of enantiomeric ... -
STRUCTURE AND PROPERTY CALCULATIONS OF AMORPHOUS CERAMICS AND GLASSES USING DENSITY FUNCTIONAL THEORY CALCULATIONS AND EMPIRICAL POTENTIAL MOLECULAR DYNAMIC SIMULATIONS
The work in this thesis involves modeling amorphous ceramics and glasses using the tools of DFT and classical MD. Systems investigated include: metal-silicate glasses (in particular HfO2- SiO2), composite coatings (comprising ... -
Structure Modeling and Property Calculations of Amorphous Materials
(2019-05-16)The demand in discovery of novel materials for a seemingly infinite list of applications is growing year by year. Even though it’s not uncommon to find the application for the material after its discovery upon experimentally ... -
Structure-Activity Relationships of Ruthenium(II) Polypyridyl Complexes with Redox-Active Intercalating Ligands: Correlation between Redox Activity, DNA Cleavage Capability and Cytotoxicity
(2015-12-10)The investigation and development of transition metal complexes as cancer chemotherapeutics has gained a lot of interest in the past few decades and has become a promising area of research. Metal complexes of platinum and ... -
Studies in Liquid and Ion Chromatography
(2017-11-30)Height- and area-based quantitation approaches reduce two-dimensional data to a single value. For a calibration set, there is a single height- or area-based quantitation equation. We introduce a new quantitation method; a ... -
Studies Of Enantiomeric Separations Using Capillary Electrophoresis
(Chemistry & Biochemistry, 2009-09-16)The focus of this thesis is on using state-of-the-art capillary electrophoresis (CE) in enantiomeric separations. Chapter 1 provides a brief introduction to enantiomeric separations using CE. Chapters 2 through 5 presents ... -
STUDIES ON ENANTIOSELECTIVE DESYMMETRIZING ALKYNE HYDROSILYLATION
(2021-08-12)This research focuses on the design and synthesis of enantioselective desymmetrizing α-hydrosilylation of propargyl alcohols to provide α-hydroxy (E)-vinylsilanes. Transition metal-catalyzed, regio-and stereoselective ... -
Studies On Reductive Horner-Wadsworth-Emmons Olefination Using Mixed Silyl Acetals
Homologation of esters to α,β-unsaturated esters is a useful transformation in organic synthesis. We have developed a new approach for the Ir-catalyzed reductive Horner-Wadsworth-Emmons olefination of esters; a one-pot ... -
Studies Toward The Enantioselective Total Synthesis Of The Martinella Alkaloids
(Chemistry & Biochemistry, 2007-08-23)This dissertation consists of two parts. The first part describes the enantioselective total synthesis of martinellic acid. The Martinella alkaloids have attracted considerable attention in the synthetic community over the ... -
Studies Towards Bioactive Imidazoles
(Chemistry & Biochemistry, 2008-04-22)The work presented in this thesis focuses on the development of an enantioselective and practical route form the total synthesis of villagorgin via haplosleridamine imidazole alkaloid containing β- carboline moiety by ... -
STUDIES TOWARDS THE TOTAL SYNTHESIS OF IMIDAZOLE-CONTAINING NATURAL PRODUCTS
(2018-09-11)Nature has inspired man in all aspects of life, chemistry included. The first antibiotic ever discovered came from nature, and since then, chemists have been probing nature for insights to guide drug discovery and development. ... -
Studies Towards The Total Synthesis Of Haploscleridamine And Ceratinadin B
In Chapter 1, we discuss the synthesis of haploscleridamine. Haploscleridamine is a novel tryptamine-derived alkaloid isolated from a sponge of the order Haplosclerida. This alkaloid inhibits cathepsin K, a cysteine protease, ... -
STUDY OF HIERARCHY AND PORE ARCHITECHTURE OF POROUS MATERIALS
(2021-04-19)Research to design, synthesize, and characterize porous materials is a rapidly growing field due to porous materials’ potential use in a wide range of applications. For any application, insights into the structure formation ... -
Supercharging and Multiple Reaction Monitoring Optimization of High Molecular Weight Intact Proteins using Triple Quadrupole Mass Spectrometry
(2019-07-17)Various supercharging agents, such as meta-nitrobenzyl alcohol, dimethyl sulfoxide, trifluoroethanol (TFE), and sulfolane were tested in different concentrations to study the effects of supercharging agents on the charge ... -
SUPERCRITIAL FLUID EXTRACTION - SUPERCRITICAL FLUID CHROMATOGRAPHY - MASS SPECTROMETRY (SFE-SFC-MS) METHOD DEVELOPMENT FOR ONLINE EXTRACTION OF COMPLEX BIOLOGICAL AND ENVIRONMENTAL MATRICES
(2021-09-03)A systematic approach to the rapid development of hyphenated online methods for supercritical fluid extraction-supercritical fluid chromatography-mass spectrometry (SFE-SFC-MS) was established for the analysis of complex ... -
Supporting Traditional Instructional Methods With A Constructivist Approach To Learning: Promoting Conceptual Change And Understanding Of Stoichiometry Using E-learning Tools
(Chemistry & Biochemistry, 2014-07-14)Stoichiometry is a fundamental topic in chemistry that measures a quantifiable relationship between atoms, molecules, etc. Stoichiometry is usually taught using expository teaching methods. Students are passively given ... -
Supramolecular Chemistry Of Nitrogen Dioxide
(Chemistry & Biochemistry, 2007-08-23)Supramolecular chemistry has been defined as "chemistry beyond molecules", and involves investigating molecular systems held together reversibly by inter-molecular forces, not by covalent bonds. This dissertation discusses ... -
Supramolecular Chemistry On Carbon Dioxide
(Chemistry, 2008-04-22)This dissertation describes approaches towards designs, syntheses, characterizations, and applications of supramolecular chemistry on carbon dioxide. Chapter 1 briefly overviews the field of supramolecular chemistry and ... -
Supramolecular Nanostructures Based On Calixarenes
(Chemistry & Biochemistry, 2007-08-23)This dissertation describes a systematic approach towards the design, synthesis, characterization, and application of calixarene-based supramolecular nanostructures. Chapter 1 briefly overviews the field of supramolecular ... -
Surface Functionalization Of Polymer Substrates And Nanoparticles Via Pulsed Plasma Polymerization Process
(Chemistry & Biochemistry, 2007-08-23)This thesis investigates the RF plasma polymerizations of chlorinated saturated linear monomer 1,1,1-trichloroethane and the dicarboxylic citraconic acid. It utilizes a variable duty cycle plasma technique to provide film ...