Browsing Department of Chemistry and Biochemistry by Author "Mandal, Subhrangsu"
Now showing items 1-7 of 7
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Cytotoxicity Studies On Metallo-salens And Their Applications In Gene Delivery
Woldemariam, Getachew Abebe (Chemistry & Biochemistry, 2009-09-16)Most of biological catalysts including nucleases are made of active metal centers. Metal complexes that are able to interact with DNA and RNA mimicking these natural nucleases will be valuable as therapeutic agents that ... -
EPIGENETIC MECHANISM OF REGULATION OF HOX GENES AND NEUROTRANSMITTERS VIA HORMONES AND LncRNA
Deb, Paromita; 0000-0002-9903-2592 (2017-08-02)Endocrine disrupting chemicals (EDCs) are classes of environmental contaminants whose exposure even at very low concentrations interfere with normal endocrine signaling and induce many adverse health effects including ... -
Epigenetics Of HOXC13 Endocrine Regulation And Its Role In Gene Expression And Tumorigenesis
Kasiri, Sahba (Chemistry & Biochemistry, 12-10-2012)HOX genes are a subgroup of homeobox containing gene superfamily and have crucial roles in cell proliferation, cell differentiation, and embryonic development. HOXC13, one of 39 identified human HOX genes, is involved in ... -
Long non-coding RNAs in inflammation, macrophage activation, and inflammatory human diseases
Chini, Avisankar; 0009-0001-5394-6516 (2023-08-28)**Please note that the full text is embargoed until 08/01/2025** Inflammation and immune signaling is central to infection and diseases. Growing evidence suggests that along with protein coding genes, long non-coding RNAs ... -
Mixed Lineage Leukemia Histone Methylases In Gene Expresion And Cancer
Mishra, Bibhu Prasad (Chemistry & Biochemistry, 2009-09-16)Histone methyl-transferases (HMTs) are key enzymes that post-translationally methylate nuclear histone proteins and play critical roles in gene expression, epigenetic regulation and diseases in eukaryotic organisms. Mixed ... -
Mixed Lineage Leukemia Histone Methylases In Hormonal Regulation Of HOX Genes And Their Disruption By Endocrine Disrupting Chemicals
Hussain, Imran (Chemistry & Biochemistry, 2014-03-10)Homeobox (HOX) genes are highly conserved family of genes that play vital roles during cell differentiation and embryogenesis. Of the 39 HOX genes present in human, HOXC6 is a critical players in mammary gland development, ... -
Mixed Lineage Luekemia Histone Methyltransferases In Hormonal Regulation Of HOXB9 And Target Gene Regulation
Shrestha, Bishakha (Chemistry & Biochemistry, 2014-09-17)Homeobox gene (HOX) genes are evolutionary conserved genes that play important roles in cell differentiation, cell proliferation and embryogenesis. HOX genes bind to the DNA via their homeodomain and act as transcription ...