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ENANTIOSELECTIVE SYNTHESIS OF AN ANTICANCER RUTHENIUM POLYPYRIDYL COMPLEX (RPC) AND INFLUENCE OF CHIRAL SELECTIVITY ON DNA PHOTOCLEAVAGE
(2017-12-08)
Ruthenium polypyridyl complexes (RPCs) represent a promising therapeiutic class of drugs for transition-metal based anticancer drug development. The complex [(phen)2Ru(tatpp)Ru(phen)2] (44+) is a RPC which has shown success ...
RHENIUM(I) COMPLEXES OF TETRAAZATETRAPYRIDOPENTACENE (TATPP): SYNTHESIS, CHARACTERIZATION, REACTIVITY, ANTICANCER POTENTIAL AND LUMINESCENT PROBE TO DETERMINE CELLULAR LOCALIZATION
(2016-05-19)
The ruthenium polypyridyl complexes [(phen)2Ru(tatpp)Ru(phen)2]4+ ([P]4+) and [(phen)2Ru(tatpp)]2+ ([MP]2+) are promising anti-tumor agents that arrest H358 NSCLC tumor growth in mouse tumor models and show cytotoxicity ...