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HIGHLY FLUORINATED, COINAGE METAL COMPLEXES OF TRIS(PYRAZOLYL)BORATES WITH ADDITIONAL ELECTRON WITHDRAWING GROUPS AND PYRAZOLATE π-STACKINGS WITH ARENES
(2016-05-11)
Tris(pyrazolyl)borates are very popular ligands in inorganic chemistry, bioinorganic chemistry, and organometallic chemistry due to their attractive properties. It is possible to extensively modify the steric and electronic ...
THE DETERMINATION OF WATER UTILIZING HEADSPACE GAS CHROMATOGRAPHY AND IONIC LIQUID STATIONARY PHASES
(2016-08-24)
Water may be the most analyzed compound in the world. It is measured, monitored and controlled in many industries and most consumer products. The moisture is regulated in products intended for human/animal consumption (e.g. ...
DESIGN AND EVALUATION OF HMP KINASE ANALOGS AS THIAMINE PATHWAY INHIBITORS
(2016-08-15)
Current bacterial chemotherapy faces an overwhelming reduction in efficacy due to an increase in bacterial resistance; resulting in a higher clinical demand for novel therapeutics and the investigation for their respective ...
APPLICATION OF NOVEL HETEROSUBSTITUTED VINYLIMIDAZOLES: AN APPROACH EN ROUTE TO THE TOTAL SYNTHESIS OF AXINELLAMINE A
(2016-05-11)
Our group is primarily interested in the total synthesis of oroidin-based pyrrole-imidazole-containing marine sponge-derived alkaloids. These pyrrole-imidazole natural products are a growing class of alkaloids with exotic ...
INTACT PROTEIN DETECTION, SEPARATION, AND QUANTITATION USING LIQUID CHROMATOGRAPHY - TRIPLE QUADRUPOLE MASS SPECTROMETRY
(2016-08-10)
There is an increasing demand for protein detection and quantitation in biological fluids for disease detection, protein therapeutics monitoring, and drug development response control. Current methods use highly sensitive ...
Advances in Separation Methodologies: Fatty Acid, Fatty Amine, Water, and Ethanol Determination by Ionic Liquid Gas Chromatography and D-Amino Acid Evaluation in Mammalian Brain by Liquid Chromatography
(2016-08-15)
This dissertation focuses on two chromatographic techniques, gas chromatography (GC) and high performance liquid chromatography (HPLC). The goal of the GC work is to describe advances in separation methodologies focusing ...
MECHANISM AND USE OF PAIRED ION ELECTROSPRAY IONIZATION (PIESI) IN HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (HPLC-MS) FOR SENSITIVE ANALYSIS OF ANIONIC COMPOUNDS
(2016-04-18)
In recent years, the paired ion electrospray ionization (PIESI) technique has been emerged as a promising alternative to overcome the inherent low sensitivity of negative ESI-MS. The current research focused on the further ...
INTRACELLULAR BIOCHEMICAL TARGETS OF RUTHENIUM POLYPYRIDYL COMPLEXES IN MULTIPLE CANCER CELL MODELS
(2016-12-16)
The ruthenium (II) polypyridyl complexes [(phen)2Ru(tatpp)Ru(phen)2]4+, RPC4 and [(phen)2Ru(tatpp)]2+, RPC3 are promising anticancer candidates due to their observed cytotoxic effect against multiple cancer cell lines. ...
RHENIUM(I) COMPLEXES OF TETRAAZATETRAPYRIDOPENTACENE (TATPP): SYNTHESIS, CHARACTERIZATION, REACTIVITY, ANTICANCER POTENTIAL AND LUMINESCENT PROBE TO DETERMINE CELLULAR LOCALIZATION
(2016-05-19)
The ruthenium polypyridyl complexes [(phen)2Ru(tatpp)Ru(phen)2]4+ ([P]4+) and [(phen)2Ru(tatpp)]2+ ([MP]2+) are promising anti-tumor agents that arrest H358 NSCLC tumor growth in mouse tumor models and show cytotoxicity ...