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AN ACTOMYOSIN DRIVEN, PRESSURE BASED ADHESION MODEL OF CONFINED GLIOBLASTOMA MULTIFORME CELL MIGRATION
(2016-05-13)
Glioblastoma multiforme (GBM) is the most aggressive and common form of glial tumors arising in the support cells of the brain. Cell migration plays a critical role in undermining the surgical resection of tumors. ...
Functional Studies of the Human Telomerase Holoenzyme
(2016-09-13)
Telomeres are the DNA structures that cap the ends of linear chromosomes. In humans, telomeres are composed of the hexameric repeats TTAGGG. The reverse transcriptase, telomerase maintains the telomeres by adding the TTAGGG ...
Localized Treatment of Malignant Melanoma Using a Modified Cellulose-Based Hydrogel Loaded with Temozolomide with Increased Safety of Human Dermal Fibroblasts and the Mechanisms Behind the Effect
(2021-08-30)
Melanoma pathophysiology is highly varied, and the initial cause of tumorigenesis is still unknown, but it is likely a combination of both epigenetic and genetic means. Further, melanoma tumors have one of the highest ...