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Now showing items 1-9 of 9
NON-INVASIVE PROFILING OF MOLECULAR MARKERS IN BRAIN GLIOMAS USING DEEP LEARNING AND MAGNETIC RESONANCE IMAGES
(2021-04-29)
Gliomas account for the most common malignant primary brain tumors in both pediatric and adult populations. They arise from glial cells and are divided into low grade and high-grade gliomas with significant differences in ...
Metabolic and Electrophysiological Effects of Transcranial Photobiomodulation (PBM) and Multi-wavelength PBM
(2021-05-28)
Photobiomodulation (PBM) with near infrared light may become a non-invasive, effective clinical tool after it is understood well for its mechanism of action. In my dissertation research, I have addressed three research ...
AN IN VITRO MODEL TO STUDY THE ROLE OF IOL: LENS CAPSULE INTERACTIONS IN POSTERIOR CAPSULE OPACIFICATION
(2021-05-05)
Posterior capsule opacification (PCO) is the most common complication associated with intraocular lens (IOL) implantation. Unfortunately, current in vitro models cannot be used to assess the potential of PCO due to their ...
Poly(lactic-co-glycolic acid) Nanoparticle Delivery of Notch Intracellular Domain Plasmid to Restore Notch Signaling
(2021-08-23)
Notch signaling is a highly conserved signaling system that is required for embryonic development and regeneration of organs. When the signal is lost, maldevelopment occurs and leads to a lethal state. Delivering exogenous ...
EVALUATION OF A PERSONAL MOBILE TRAINER SYSTEM DESIGNED FOR FACILITATING EXERCISE THERAPY FOR TRAUMATIC BRAIN INJURY PATIENTS
(2021-08-16)
There are no effective pharmacological agents that can prevent or treat post-TBI cognitive deterioration. Previous research has shown that exercise can be an effective means of enhancing the patients condition with mild ...
Localized Treatment of Malignant Melanoma Using a Modified Cellulose-Based Hydrogel Loaded with Temozolomide with Increased Safety of Human Dermal Fibroblasts and the Mechanisms Behind the Effect
(2021-08-30)
Melanoma pathophysiology is highly varied, and the initial cause of tumorigenesis is still unknown, but it is likely a combination of both epigenetic and genetic means. Further, melanoma tumors have one of the highest ...
PORCINE NEONATAL HEART EXTRACELLULAR MATRIX AS A REGENERATION PLATFORM
(2021-08-16)
Each year, an estimated 620,000 Americans have new heart attack and suffer from myocardial infarction (MI) that results in massive heart cell death and decrease in heart function. Various therapeutic strategies, such as ...
BIOMECHANICAL STUDIES OF DEVELOPING ZEBRAFISH HEART IN-VIVO
(2021-05-05)
The heart is an electrically controlled mechanical pump that provides the cardiac output required by the body to function properly and flexibly adapts to changing demand and working conditions. In vertebrate embryos, the ...
Designing and advancing contrast agents for ultrasound-switchable fluorescence imaging
(2021-12-09)
Fluorescence imaging is a remarkable tool for molecular targeting and multicolor imaging, but it suffers from poor resolution in centimeters-deep tissues. The recently developed ultrasound-switchable fluorescence (USF) ...