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CELL-FREE STUDIES OF CATALYTIC DNA CLEAVAGE BY RUTHENIUM POLYPYRIDYL COMPLEXES (RPCS) CONTAINING REDOX-ACTIVE INTERCALATING LIGANDS, ENANTIOMERIC SEPARATION AND SEMI-PREP SCALE PURIFICATION OF RPCS
(2018-08-28)
Herein, we report the ruthenium (II) polypyridyl complexes (RPCs), [(phen)₂Ru(tatpp)] ²⁺ (3²⁺) and [(phen)₂Ru(tatpp)Ru(phen)₂] ⁴⁺ (4⁴⁺) are shown to cleave DNA in cell-free studies in the presence of a mild reducing agent, ...
Structure Modeling and Property Calculations of Amorphous Materials
(2019-05-16)
The demand in discovery of novel materials for a seemingly infinite list of applications is growing year by year. Even though it’s not uncommon to find the application for the material after its discovery upon experimentally ...
SYNTHESIS AND REACTIVITY OF π-CONJUGATED TRIAZENES
(2019-05-02)
The triazene functional group has found numerous applications in organic and medicinal chemistry, with several important chemotherapeutic drugs containing this functionality. In spite of this, the reactivity of π-conjugated ...
ONLINE BIOANALYTICAL MASS SPECTROMETRY METHODS FOR ANALYSIS OF SMALL AND LARGE BIOMOLECULES USING ONE- AND TWO-DIMENSIONAL LIQUID CHROMATOGRAPHY
(2018-12-06)
In recent years, the innovation in biomarkers and biotherapeutics has increased the demand for state-of-the-art analytical platforms to achieve reliable and accurate discoveries and quantitative analysis methods. The ...
Dynamics and Control of Jumping Legged Robot
(2018-08-13)
This research aims to studying the agility of legged robots particularly their interactions with the ground and achieve a jumping motion by using an operational space controller.
Methods were developed to first formulate ...
Approaches Toward the Total Synthesis of Oroidin Alkaloids:Nagelamide A, C and Ageliferin
(2018-05-25)
Nagelamides and ageliferin are oroidin-derived alkaloids which have gained the attention of the scientific community, because of their significant biological activity as well as the unprecedented structural diversity. Our ...
Studies in Liquid and Ion Chromatography
(2017-11-30)
Height- and area-based quantitation approaches reduce two-dimensional data to a single value. For a calibration set, there is a single height- or area-based quantitation equation. We introduce a new quantitation method; a ...
Organizational Socialization: The Role of Onboarding in Employee Longevity
(2018-09-07)
This study proposed testing a model linking employees’ onboarding experience within the first three months at an organization with their tenure through the mediators of perceived supervisor (PSS) and organizational support ...
STUDIES TOWARDS THE TOTAL SYNTHESIS OF IMIDAZOLE-CONTAINING NATURAL PRODUCTS
(2018-09-11)
Nature has inspired man in all aspects of life, chemistry included. The first antibiotic ever discovered came from nature, and since then, chemists have been probing nature for insights to guide drug discovery and development. ...
IDENTIFICATION OF PROTEOLYTIC CLEAVAGE AND ARGININE MODIFICATIONS BY CHEMICAL LABELING AND MASS SPECTROMETRY
(2017-12-06)
Post-translational modification of proteins plays a significant role in the regulation of cellular processes. During the translation, process proteins undergo different modifications, which are known as post-translational ...