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Now showing items 11-20 of 32
AN IN VITRO MODEL TO STUDY THE ROLE OF IOL: LENS CAPSULE INTERACTIONS IN POSTERIOR CAPSULE OPACIFICATION
(2021-05-05)
Posterior capsule opacification (PCO) is the most common complication associated with intraocular lens (IOL) implantation. Unfortunately, current in vitro models cannot be used to assess the potential of PCO due to their ...
Poly(lactic-co-glycolic acid) Nanoparticle Delivery of Notch Intracellular Domain Plasmid to Restore Notch Signaling
(2021-08-23)
Notch signaling is a highly conserved signaling system that is required for embryonic development and regeneration of organs. When the signal is lost, maldevelopment occurs and leads to a lethal state. Delivering exogenous ...
Novel Quantification of Neurovascular Coupling (NVC) to Predict Brain Injury in Neonates with Hypoxic Ischemic Encephalopathy
(2020-09-04)
Birth asphyxia is a global burden in clinical neonatal care. It results from deprivation of oxygen to a newborn infant that lasts too long during the birth causing physical harm to the brain. The asphyxia insult impairs ...
Machine Learning and Deep Learning Applications in Neuroimaging
(2020-08-20)
Deep Learning (DL) tools have the potential to analyze large datasets and extract meaningful insights to enhance patient outcomes. Radiological images such as MRI and CT, often contain complex patterns that can be difficult ...
Targeting the Oligomannose Biomarker Present on Distinct Subsets of Non-Hodgkin Lymphomas
(2020-09-04)
Subtypes of B cell non-Hodgkin’s lymphomas, including follicular lymphomas, have shown a unique high oligomannose presentation on their immunoglobulins that will interact with natural receptors of the innate immunity, ...
PHOTOBIOMODULATION AND STEM CELL DIFFERENTIATION: APPLICATION TO MODULATE ADIPOGENESIS THROUGH CELLULAR AND NUCLEAR MORPHOLOGY
(2020-05-28)
Mesenchymal stem cells (MSCs) are of great interest in regenerative medicine due
to their capability to self-renew and differentiate to various lineages. Typically,
differentiation to specific cell types has relied on ...
Whole-head functional brain imaging of economic risk decision making and transcranial photobiomodulation with fNIRS and EEG
(2020-09-08)
Functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG) are two non-invasive brain imaging or mapping modalities that allow us to measure cerebral hemodynamic and electrophysiological changes in the ...
Microchannel technology in cancer cell confined-migration study and its application in drug screening
(2020-08-10)
PDMS-based microchannel device has been explored to extend the basic platform for three-dimensional (3D) culture models of cell motility study because of its relevant stiffness and designable shape. Moreover, it is easy ...
MODULATION OF PHYSIOLOGIC RESPONSES OF INSULIN SECRETING CELLS USING ELECTRICAL AND PHOTOSTIMULATION
(2020-09-01)
Islet transplantation is a surgical procedure aimed at providing insulin independence to those suffering with Type I diabetes. Prior to implantation, a therapeutic window exists ex vivo where the cells can be treated in ...
The Biomechanics of Cardiac Elastin and its Role in Bioengineering
(2020-09-09)
Elastin is an essential structural protein responsible for the elasticity of many tissues, including skin, lungs, blood vessels, and other highly dynamic tissues and organs in the body. In the heart, cardiac elastin has ...