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Stimuli-Responsive Peptide Self-Assembly for Therapeutic Delivery
(2022-08-16)
Peptide self-assembly offers an effective method to generate supramolecular
nanomaterials with much higher stability than traditional monomeric peptides. The materials
exhibit well-organized hierarchical structures and ...
STUDY OF HIERARCHY AND PORE ARCHITECHTURE OF POROUS MATERIALS
(2021-04-19)
Research to design, synthesize, and characterize porous materials is a rapidly growing field due to porous materials’ potential use in a wide range of applications. For any application, insights into the structure formation ...
Probing Short-Range Structural Distortion of Stereochemically Active Lone Pairs in Extended Solid-State Materials
(2022-12-20)
The structural and electronic effects of the lone pairs play an important role in magnetic, photocatalytic, and semiconducting behaviors of materials. Investigating the role of stereochemically active ns2 lone pairs derived ...
Development of Colorimetric and Fluorescent Antibiotic Biosensors and Synthesis of Drug-Related Biomimetic Molecules for Calcium Carbonate Polymorph Control and Stabilization
(2022-12-19)
Polydiacetylene (PDA) polymers are conjugated macromolecules with desirable sensing
properties. The presence of alternate double and triple bonds (en-yne subunits)
generates electron delocalization in the PDA backbone, ...
NEW STRATEGIES FOR HYDROSILYLATION OF PROPARGYL ALCOHOLS, OLEFIN POLYMERIZATION AND ON-CHIP ORGANIC SYNTHESIS
(2020-08-11)
The research described in this dissertation is on three different projects namely i) design and synthesis of traceless hydrosilyl acetal-directed, exo-syn hydrosilylation of propargyl alcohols to produce α-hydroxy ...
SYNTHESIS, STUDY, AND APPLICATIONS OF HIGHLY FLUORINATED COPPER PYRAZOLATE COMPLEXES OF SMALL ALKENE, ALKYNES AND CARBON MONOXIDE
(2020-07-17)
Trinuclear copper pyrazolate complexes (copper trimers) function as excellent precursors to synthesize multinuclear complexes of copper. Using highly fluorinated pyrazolates as supporting ligands, we have successfully ...
MECHANISTIC STUDIES OF F420-DEPENDENT ENZYMES BY KINETIC ANALYSIS
(2021-08-10)
The focus of this research is to elucidate the catalytic mechanism of F420-dependent enzymes using F420-dependent glucose-6-phosphate dehydrogenase (FGD) from Mycobacteria tuberculosis (Mtb) and F420H2:NADP+ Oxidoreductase ...
Synthetic studies on oxidative dearomatization reactions and applications in synthesis of the KB343 core structure, and investigation of bioactive thiazolidines
(2022-08-16)
Natural products have inspired researchers over the years due to their complexity and biological activity. Organic chemists have made great efforts to investigate new unambiguous methodologies toward the synthesis of these ...
FLUORINATED ALCOHOL INDUCED SUPRAMOLECULAR BIPBASIC SYSTEMS IN PROTEOMICS AND LIPIDOMICS
(2021-05-28)
The Fluoroalcohol induced Supramolecular Biphasic (FAiS-BP) systems are composed of a supramolecular phase which is a highly concentrated mixture of a fluoroalcohol and an amphiphile, and a separate aqueous-rich phase. The ...
EXPEDITIOUS APPROACH TO 3,3’-BIS-SILYL BINOLS, BIPHENOLS, AND 3,3’-BIS-SILYL PHOSPHORAMIDITES ENABLED BY CATALYTIC C–H SILYLATION WITH A TRACELESS ACETAL DIRECTING GROUP
(2021-05-10)
The research described in this dissertation is on two different projects namely i) Syntheses of 3,3’-bis functionalized BINOL and biphenol compounds, ii) Syntheses of 3,3’-bis silyl-BINOL-based phosphoramidites. The first ...