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Engineering Elastic and Functional Electrospun Nano-Fibers for Potential Heart Repair
(2022-08-17)
In the United States and around the world, cardiovascular disease (CVD) has been one of the main causes of death since 1921, responsible for approximately 1 in 4 deaths domestically. Myocardial infarction (MI), or commonly ...
ADVANCING THE RADIATION ONCOLOGY CLINIC WITH MOTION MANAGEMENT AND AUTOMATIC TREATMENT PLANNING
(2022-06-09)
The leading cause of premature death (death under the age of 70) is cancer. The top five cancers for both male and female are: lung, colorectum, pancreas, breast cancer, and prostate. In 2020 there was an estimated 19.3 ...
IMPACT OF MUSCULAR FATIGUE AND ITS MODULATION USING TRANSCRANIAL PHOTOBIOMODULATION (tPBM) ON THE HUMAN BRAIN MEASURED BY FUNCTIONAL NEAR-INFRARED SPECTROSCOPY (fNIRS)
(2020-07-22)
When performing exercise, the brain must register and simultaneously integrate input from feedforward (i.e., central command) and feedback (e.g., exercise pressor reflex) neural mechanisms to make appropriate cardiovascular ...
Nanoparticle-Mediated Controlled Myocardial Drug Delivery: A New Treatment for Hypertrophic Cardiomyopathy
(2020-09-04)
Hypertrophic cardiomyopathy (HCM) is a genetic disease of the sarcomere, resulting in overgrowth of the septum that separates the left and right ventricles. HCM can affect as many as 1/200 people, making it the most common ...
NANOPARTICLE-BASED APPROACHES IN CARDIOVASCULAR DISEASES
(2020-08-14)
Percutaneous coronary intervention (PCI) such as balloon angioplasty and stent placement are commonly employed for myocardial revascularization. These strategies, however, injure the arterial wall initiating a cascade of ...
In vivo ultrasound-switchable fluorescence imaging and its applications
(2020-08-17)
The conventional fluorescence imaging has limited spatial resolution in centimeters-deep tissue because of the tissue’s high scattering property. Ultrasound-switchable fluorescence (USF) imaging, a new imaging technique, ...
Electrophysiological, Hemodynamic, and Metabolic Effects of Transcranial Photobiomodulation (tPBM) on Topographical and Physiological Connectivity in the Human Brain
(2022-08-17)
Transcranial photobiomodulation (tPBM) targets the human brain with near-infrared (NIR) light and is shown to affect human cognitive performance and neural electrophysiological activity as well as concentration changes of ...
Mapping of Electroencephalogram (EEG) Responses to Newsvendor Decision Model and Cerebral Hemodynamic Responses to Transcranial Photobiomodulation (tPBM) in Humans
(2022-05-17)
Decision-making is one of the most critical activities of human beings. Various studies have investigated the brain responses to a variety of decision tasks by deploying the EEG data. The first aim of my dissertation was ...
NON-INVASIVE PROFILING OF MOLECULAR MARKERS IN BRAIN GLIOMAS USING DEEP LEARNING AND MAGNETIC RESONANCE IMAGES
(2021-04-29)
Gliomas account for the most common malignant primary brain tumors in both pediatric and adult populations. They arise from glial cells and are divided into low grade and high-grade gliomas with significant differences in ...
Metabolic and Electrophysiological Effects of Transcranial Photobiomodulation (PBM) and Multi-wavelength PBM
(2021-05-28)
Photobiomodulation (PBM) with near infrared light may become a non-invasive, effective clinical tool after it is understood well for its mechanism of action. In my dissertation research, I have addressed three research ...